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来自……茎皮的具有抗菌和抗氧化潜力的黄酮类化合物。 (你提供的原文不完整,句末缺少具体植物名称等关键信息)

Flavonoids with antibacterial and antioxidant potentials from the stem bark of .

作者信息

Achika J I, Ayo R G, Oyewale A O, Habila J D

机构信息

Department of Chemistry, Federal University, Lokoja, Kogi State, Nigeria.

Department of Chemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.

出版信息

Heliyon. 2020 Feb 11;6(2):e03381. doi: 10.1016/j.heliyon.2020.e03381. eCollection 2020 Feb.

Abstract

Two flavonol glycosides; U1: naringenin-7--glucoside and U2: kaempferol-3--glucoside were isolated for the first time, from ethyl acetate fraction of the stem bark of a traditional medicinal plant called . IR and NMR spectroscopy were used to elucidate the structures of the isolated compound. The two compounds were active against the 7 tested microorganisms; and The zones of inhibition of the compounds ranged from 16 to 23 mm. The MIC value was as low as 6.25 μg/mL against and . The radical scavenging activity of compound U1 and U2 was 80 and 85 % at 240 μg/mL, while that of the standard drug was 98% at 240 μg/mL. The results show an existent possibility of using the plant for the treatment of microbial diseases.

摘要

首次从一种名为[具体植物名称未给出]的传统药用植物茎皮的乙酸乙酯部位分离出两种黄酮醇苷;U1:柚皮素-7-O-葡萄糖苷和U2:山奈酚-3-O-葡萄糖苷。采用红外光谱和核磁共振光谱对分离得到的化合物结构进行了鉴定。这两种化合物对7种受试微生物具有活性;化合物的抑菌圈范围为16至23毫米。对[具体微生物名称未给出]和[具体微生物名称未给出]的最低抑菌浓度值低至6.25μg/mL。化合物U1和U2在240μg/mL时的自由基清除活性分别为80%和85%,而标准药物在240μg/mL时的自由基清除活性为98%。结果表明该植物具有用于治疗微生物疾病的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ab5/7016232/a6da462d4618/gr1.jpg

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