Androutsopoulou Chrysa, Christopoulou Spyridoula D, Hahalis Panagiotis, Kotsalou Chrysoula, Lamari Fotini N, Vantarakis Apostolos
Department of Public Health, Faculty of Medicine, University of Patras, 26504 Patras, Greece.
Laboratory of Pharmacognosy & Chemistry of Natural Products, Department of Pharmacy, University of Patras, 26504 Patras, Greece.
Pathogens. 2021 Apr 19;10(4):494. doi: 10.3390/pathogens10040494.
Essential oils (EOs) and extracts of rose geranium () and petals of rose () have been fully characterized in terms of composition, safety, antimicrobial, and antiviral properties. They were analyzed against , serovar Typhimurium, , , and Adenovirus 35. Their toxicity and life span were also determined. EO of (5%) did not retain any antibacterial activity (whereas at 100% it was greatly effective against ), had antifungal activity against , and significant antiviral activity. Rose geranium extract (dilutions 25-90%) (/) had antifungal and antibacterial activity, especially against , and dose-dependent antiviral activity. Rose petals EO (5%) retains low inhibitory activity against and Typhimurium growth (about 20-30%), antifungal activity, and antiviral activity for medium to low virus concentrations. Rose petals extract had significant antibacterial activity at dilutions of 25-90%, especially against and Typhimurium, antifungal, and the most potent antiviral activity. None of the EOs and extracts were toxic in dilutions of up to 5% and 90%, respectively. Finally, all materials had a life span of more than eight weeks. These results support the aspect that rose petals and rose geranium EOs, and extracts, have beneficial antimicrobial and antiviral properties and they can be used as natural preservatives.
玫瑰天竺葵（）和玫瑰（）花瓣的精油（EOs）及提取物在成分、安全性、抗菌和抗病毒特性方面已得到充分表征。对它们针对、鼠伤寒沙门氏菌血清型、、和腺病毒35进行了分析。还测定了它们的毒性和保质期。玫瑰天竺葵精油（5%）没有保留任何抗菌活性（而100%时对有显著效果），对有抗真菌活性，且有显著的抗病毒活性。玫瑰天竺葵提取物（25 - 90%稀释度）（/）有抗真菌和抗菌活性，尤其对，且有剂量依赖性抗病毒活性。玫瑰花瓣精油（5%）对和鼠伤寒沙门氏菌生长保留低抑制活性（约20 - 30%）、抗真菌活性以及对中低病毒浓度的抗病毒活性。玫瑰花瓣提取物在25 - 90%稀释度时有显著抗菌活性，尤其对和鼠伤寒沙门氏菌、抗真菌活性以及最强的抗病毒活性。分别在高达5%和90%的稀释度下，没有一种精油和提取物有毒性。最后，所有材料的保质期超过八周。这些结果支持玫瑰花瓣和玫瑰天竺葵精油及提取物具有有益的抗菌和抗病毒特性且可作为天然防腐剂的观点。
