Turlington B S, Edwards W D
Division of Pathology, Mayo Clinic, Rochester, Minnesota.
Am J Cardiovasc Pathol. 1988;2(2):151-7.
In endomyocardial specimens from 100 normal hearts from autopsy, the mean number of mast cells per high-power field was calculated. A peak occurred in the third decade and was more marked in women than men. In the fourth through seventh decades, mean values were greater in men than women. For both sexes, the number of mast cells in the left ventricle tended to exceed that in the right ventricle. The number of mast cells was similarly determined in 92 diseased hearts. The range of mean values overlapped considerably with that of normal hearts. The highest mean values occurred in subjects with mast cell neoplasia, giant cell myocarditis, and lymphocytic myocarditis; and the lowest occurred in the group with amyloidosis. The values in patients with eosinophilic myocarditis did not differ appreciably from normal. Increased numbers of mast cells tended to be associated with areas of fibrosis more than with inflammatory infiltrates.
在取自100例正常心脏尸检的心肌内膜标本中，计算了每个高倍视野下肥大细胞的平均数。肥大细胞数量在第三个十年出现峰值，且女性比男性更明显。在第四个至第七个十年中，男性的平均值高于女性。对于两性而言，左心室中的肥大细胞数量往往超过右心室。在92例患病心脏中同样测定了肥大细胞数量。平均值范围与正常心脏有相当大的重叠。平均值最高出现在肥大细胞瘤、巨细胞心肌炎和淋巴细胞性心肌炎患者中；最低出现在淀粉样变性组。嗜酸性粒细胞性心肌炎患者的值与正常相比无明显差异。肥大细胞数量增加往往与纤维化区域相关，而不是与炎性浸润相关。
