Foley D A, Edwards W D
Division of Pathology, Mayo Clinic, Rochester, Minnesota.
Am J Cardiovasc Pathol. 1988;2(2):145-9.
From 100 normal human hearts, evenly distributed by age and sex, 5 endomyocardial samples were obtained from the septal surface of each ventricle with a cardiac bioptome. In each case, from both ventricles, the number of lymphocytes, eosinophils, plasma cells, and neutrophils was counted in 10 high-power (x400) microscopic fields, and the mean number of each type of leukocyte was calculated. In 95% of the 2,000 high-power fields, the number of interstitial lymphocytes was less than 5.0. Moreover, in all but one heart, the mean number of lymphocytes was less than 4.0. The mean number of eosinophils was 0.0-0.1 and of plasma cells was 0.0-0.3. The median number of neutrophils was 0.6. Recognition of the normal number of leukocytes in the heart may help to minimize false positive interpretations of myocarditis in biopsy specimens of endomyocardial tissue from living patients.
从100颗年龄和性别分布均匀的正常人体心脏中，使用心脏活检钳从每个心室的间隔表面获取5份心内膜样本。在每种情况下，对两个心室的10个高倍（×400）显微镜视野中的淋巴细胞、嗜酸性粒细胞、浆细胞和中性粒细胞数量进行计数，并计算每种白细胞的平均数。在2000个高倍视野中的95%中，间质淋巴细胞数量少于5.0。此外，除了一颗心脏外，所有心脏的淋巴细胞平均数均少于4.0。嗜酸性粒细胞的平均数为0.0 - 0.1，浆细胞的平均数为0.0 - 0.3。中性粒细胞的中位数为0.6。了解心脏中正常白细胞数量可能有助于减少对活体患者心内膜组织活检标本中心肌炎的假阳性解读。
