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一名78岁女性，患有弥漫性瘙痒性皮疹和掌跖脱屑。

A 78-Year-Old Female with a Diffuse Pruritic Rash and Palmoplantar Desquamation.

作者信息

Molina Gabriel E, Danesh Melissa J, Foreman Ruth K, Kroshinsky Daniela

机构信息

Harvard Medical School, Boston, Massachusetts, USA.

Harvard Combined Dermatology Residency Program, Boston, Massachusetts, USA.

出版信息

Dermatopathology (Basel). 2020 Jan 22;6(4):241-245. doi: 10.1159/000503745. eCollection 2019 Oct-Dec.

DOI:10.1159/000503745
PMID:32083061
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7011743/
Abstract

Mycosis fungoides, the most common cutaneous T-cell lymphoma, is known to exhibit varied clinical presentations and mimic many other dermatoses. This morphological heterogeneity can often lead to initial misdiagnoses resulting in significant delays from symptom onset to diagnosis. We report a case of mycosis fungoides imitating clinical and histopathological features of erythema annulare centrifugum.

摘要

蕈样肉芽肿是最常见的皮肤T细胞淋巴瘤，已知其临床表现多样，可模仿许多其他皮肤病。这种形态学异质性常常导致最初的误诊，从而使从症状出现到诊断的时间显著延迟。我们报告一例蕈样肉芽肿模仿离心性环状红斑的临床和组织病理学特征的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/ebb200cb8907/dpa-0006-0241-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/2ec219982dd4/dpa-0006-0241-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/5878cc4c7c1a/dpa-0006-0241-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/ebb200cb8907/dpa-0006-0241-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/2ec219982dd4/dpa-0006-0241-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/5878cc4c7c1a/dpa-0006-0241-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65b7/7011743/ebb200cb8907/dpa-0006-0241-g03.jpg

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本文引用的文献

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Actas Dermosifiliogr. 2017 Apr;108(3):192-208. doi: 10.1016/j.ad.2016.08.009. Epub 2016 Nov 18.
2
Erythema Annulare Centrifugum: Analysis of Associated Diseases and Clinical Outcomes according to Histopathologic Classification.离心性环状红斑：根据组织病理学分类对相关疾病及临床结局的分析
Ann Dermatol. 2016 Apr;28(2):257-9. doi: 10.5021/ad.2016.28.2.257. Epub 2016 Mar 31.
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Erythema annulare centrifugum-like mycosis fungoides after unrelated bone marrow transplantation.
Br J Haematol. 2015 Jul;170(2):140. doi: 10.1111/bjh.13489. Epub 2015 May 18.
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Review of the treatment of mycosis fungoides and Sézary syndrome: A stage-based approach.蕈样肉芽肿和塞扎里综合征的治疗综述：基于分期的方法。
Int J Health Sci (Qassim). 2013 Jun;7(2):220-39.
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Prevalence and severity of pruritus in cutaneous T cell lymphoma.皮肤 T 细胞淋巴瘤的瘙痒发生率和严重程度。
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Pruritus in cutaneous T-cell lymphoma: a review.皮肤 T 细胞淋巴瘤的瘙痒：综述。
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Erythema annulare centrifugum-like mycosis fungoides.环状离心性红斑样蕈样肉芽肿。
Australas J Dermatol. 2011 Nov;52(4):e11-3. doi: 10.1111/j.1440-0960.2010.00683.x. Epub 2010 Aug 24.
8
Mycosis fungoides mimicking an annular erythema.蕈样肉芽肿样表现为环状红斑。
Clin Exp Dermatol. 2009 Dec;34(8):e581-3. doi: 10.1111/j.1365-2230.2009.03249.x. Epub 2009 May 26.
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Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases.美国皮肤淋巴瘤的发病模式：一项基于人群的3884例病例研究。
Blood. 2009 May 21;113(21):5064-73. doi: 10.1182/blood-2008-10-184168. Epub 2009 Mar 11.
10
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