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[抗坏血酸和抗坏血酸钠对1,2-二甲基肼诱导的CBA小鼠子宫癌发生的修饰作用]

[Modifying effect of ascorbic acid and sodium ascorbate on uterine carcomogenesis induced by 1,2-dimethylhydrazine in CBA mice].

作者信息

Trukhanova L S

出版信息

Eksp Onkol. 1988;10(5):65-6.

PMID:3208694
Abstract

Administration of ascorbic acid (0.3% in drinking water) inhibited the promoting effect of estradiol dipropionate on the 1,2-dimethylhydrazine-induced uterine sarcomogenesis in CBA mice. However administration of sodium ascorbate intensified the promoting effect of estradiol on the uterine sarcomogenesis, as evidenced by the shortening of the periods of tumour incidence.

摘要

给予抗坏血酸(饮用水中含0.3%)可抑制二丙酸雌二醇对1,2-二甲基肼诱导的CBA小鼠子宫肉瘤发生的促进作用。然而,给予抗坏血酸钠会增强雌二醇对子宫肉瘤发生的促进作用,肿瘤发生率出现时间缩短即证明了这一点。

相似文献

1
[Modifying effect of ascorbic acid and sodium ascorbate on uterine carcomogenesis induced by 1,2-dimethylhydrazine in CBA mice].[抗坏血酸和抗坏血酸钠对1,2-二甲基肼诱导的CBA小鼠子宫癌发生的修饰作用]
Eksp Onkol. 1988;10(5):65-6.
2
[Effect of estradiol dipropionate on the development of uterine sarcoma induced by 1,2-dimethylhydrazine in mice].[二丙酸雌二醇对1,2-二甲基肼诱导的小鼠子宫肉瘤发生发展的影响]
Vopr Onkol. 1989;35(1):52-7.
3
Modifying effect of ascorbic acid and sodium ascorbate on the promoting stage of uterine sarcomogenesis induced in CBA mice by 1,2-dimethylhydrazine and estradiol-dipropionate.抗坏血酸和抗坏血酸钠对1,2 - 二甲基肼和二丙酸雌二醇诱导的CBA小鼠子宫肉瘤发生促进阶段的修饰作用。
Cancer Lett. 1991 Jan;56(1):29-35. doi: 10.1016/0304-3835(91)90190-s.
4
[Effect of ascorbic acid on the induction of uterine sarcomas in mice].[抗坏血酸对小鼠子宫肉瘤诱导的影响]
Vopr Onkol. 1987;33(11):53-7.
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[The inhibitory effect of ascorbic acid on the estrogen-stimulated promotion of uterine sarcoma development in mice].[抗坏血酸对雌激素刺激促进小鼠子宫肉瘤发展的抑制作用]
Vopr Onkol. 1990;36(5):563-7.
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[Stimulating action of estradiol dipropionate on uterine sarcomagenesis induced by 1,2-dimethylhydrazine in mice].[二丙酸雌二醇对1,2-二甲基肼诱导的小鼠子宫肉瘤发生的刺激作用]
Biull Eksp Biol Med. 1980 Nov;90(11):599-600.
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[Effects of cortiphen and cyclophosphamide in uterine sarcoma induced primarily by 1,2-dimethylhydrazine and estradiol dipropionate in CBA mice].
Eksp Onkol. 1990;12(1):68-70.
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[Effect of neonatal androgenization on uterine sarcomagenesis induced by 1,2-dimethylhydrazine in female CBA mice].[新生期雄激素化对1,2 - 二甲基肼诱导雌性CBA小鼠子宫肉瘤发生的影响]
Biull Eksp Biol Med. 1983 Oct;96(10):91-2.
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Eksp Onkol. 1986;8(3):31-2.
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