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分析针对弗罗茨瓦夫大学医院重症监护病房治疗患者的器官功能无效维持的管理方案。

Analysis of management protocols regarding ineffective maintenance of organ functions in patients treated at the Intensive Care Unit of the University Hospital in Wroclaw.

机构信息

Department of Anesthesiology and Intensive Therapy, Wroclaw Medical University, Wroclaw, Poland.

出版信息

Anaesthesiol Intensive Ther. 2020;52(1):3-9. doi: 10.5114/ait.2020.92990.

Abstract

BACKGROUND

Prolonged support of organ functions without therapeutic benefit represents a serious problem of therapy in intensive care units (ICUs). This kind of treatment, called "futile therapy", prolongs the process of dying and should be avoided. In Poland, the guidelines and protocol defining the best clinical practice for the avoidance of futile therapy in ICUs was published in 2014. The aim of study was to analyse the protocols concerning futile therapy in the general ICU in the University Hospital in Wrocław, Poland during the years 2015-2018.

METHODS

The content of protocols was analysed. The protocols contained information on clinical problems, ethical and social aspects, data on communication with relatives, and therapeutic procedures regarded as futile and consequently withheld or withdrawn.

RESULTS

During the study 1660 patients were treated in the ICU, of whom 557 patients died. Protocols regarding futile therapy were analysed in 146 patients. The diagnosis before starting the protocol was multiorgan failure (56%), permanent CNS injury (39%), respiratory failure (3%), and circulatory failure (2%). The withholding of therapeutic procedures was preferred, and the cases of withdrawal were rare. All patients with protocols died during hospital stay, 81.5% of them in the ICU.

CONCLUSIONS

The protocols concerning futile therapy were instituted in 1 in 10 patients treated in the ICU in Wrocław, which comprised was nearly one-fifth of all ICU deaths. The withholding of futile therapeutic procedures was preferred in comparison to withdrawing. Communication with relatives was essential to the process of avoiding futile therapy.

摘要

背景

在重症监护病房(ICU)中,没有治疗益处而延长器官功能的支持代表着治疗的严重问题。这种治疗被称为“无效治疗”,延长了死亡过程,应予以避免。在波兰,2014 年发布了指南和方案,为 ICU 中避免无效治疗规定了最佳临床实践。本研究的目的是分析 2015 年至 2018 年期间波兰弗罗茨瓦夫大学医院普通 ICU 中无效治疗的方案。

方法

分析方案的内容。方案中包含临床问题、伦理和社会方面、与亲属沟通的数据,以及被认为无效并因此被保留或撤回的治疗程序。

结果

在研究期间,1660 名患者在 ICU 接受治疗,其中 557 名患者死亡。分析了 146 名患者的无效治疗方案。开始方案前的诊断为多器官衰竭(56%)、永久性 CNS 损伤(39%)、呼吸衰竭(3%)和循环衰竭(2%)。首选保留治疗程序,撤回的情况很少见。所有有方案的患者都在住院期间死亡,其中 81.5%死于 ICU。

结论

在弗罗茨瓦夫 ICU 接受治疗的 10 名患者中,有 1 名患者制定了无效治疗方案,占 ICU 死亡人数的近五分之一。与撤回相比,更倾向于保留无效的治疗程序。与亲属沟通对于避免无效治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce60/10173140/a23c0aa7ba3a/AIT-52-39877-g001.jpg

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