Department of Entomology, Center for Pollinator Research, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA.
Department of Biology, York University, Toronto, ON, Canada.
Nat Rev Genet. 2020 May;21(5):277-291. doi: 10.1038/s41576-020-0216-1. Epub 2020 Feb 25.
Declines in bee populations across the world threaten food security and ecosystem function. It is currently not possible to routinely predict which specific stressors lead to declines in different populations or contexts, hindering efforts to improve bee health. Genomics has the potential to dramatically improve our ability to identify, monitor and predict the effects of stressors, as well as to mitigate their impacts through the use of marker-assisted selection, RNA interference and potentially gene editing. Here we discuss the most compelling recent applications of genomics to investigate the mechanisms underpinning bee population declines and to improve the health of both wild and managed bee populations.
全球蜜蜂数量的减少威胁到了粮食安全和生态系统功能。目前,人们还无法常规性地预测哪些特定的压力因素会导致不同种群或环境下的蜜蜂数量减少,这阻碍了人们改善蜜蜂健康的努力。基因组学有潜力极大地提高我们识别、监测和预测压力因素影响的能力,并通过使用标记辅助选择、RNA 干扰和潜在的基因编辑来减轻其影响。在这里,我们讨论了基因组学在研究导致蜜蜂种群减少的机制以及改善野生和管理蜜蜂种群健康方面的最引人注目的最新应用。