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僧人脑龄与脑区容积的纵向 MRI 研究。

BrainAGE and regional volumetric analysis of a Buddhist monk: a longitudinal MRI case study.

机构信息

Waisman Center, UW-Madison, USA.

McLean Hospital, Harvard Medical School, USA.

出版信息

Neurocase. 2020 Apr;26(2):79-90. doi: 10.1080/13554794.2020.1731553. Epub 2020 Feb 26.

Abstract

Yongey Mingyur Rinpoche (YMR) is a Tibetan Buddhist monk, and renowned meditation practitioner and teacher who has spent an extraordinary number of hours of his life meditating. The brain-aging profile of this expert meditator in comparison to a control population was examined using a machine learning framework, which estimates "brain-age" from brain imaging. YMR's brain-aging rate appeared slower than that of controls suggesting early maturation and delayed aging. At 41 years, his brain resembled that of a 33-year-old. Specific regional changes did not differentiate YMR from controls, suggesting that the brain-aging differences may arise from coordinated changes spread throughout the gray matter.

摘要

永义明觉仁波切(YMR)是一位藏传佛教僧侣,也是一位著名的冥想修行者和导师,他一生中有大量时间冥想。本研究采用机器学习框架,通过脑影像来估计“脑龄”,以比较这位专业冥想者与对照组的大脑衰老特征。与对照组相比,YMR 的大脑衰老速度似乎较慢,这表明他的大脑成熟较早,衰老较晚。41 岁时,他的大脑与 33 岁的人相似。特定的区域变化并不能将 YMR 与对照组区分开来,这表明大脑衰老的差异可能源于整个灰质的协调变化。

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