Heinsberg Lacey W, Conley Yvette P
Annu Rev Nurs Res. 2019 Dec 23;38(1):35-52. doi: 10.1891/0739-6686.38.35.
Nurse scientists are ideally positioned to perform environmental health research and it is critical that the role of omics in the complex relationships between environmental exposures and an individual's unique physiology in human health outcomes be appreciated. Importantly, omics can offer nurse scientists a tool to measure exposure, demonstrate molecular phenotypic changes associated with exposure, and potentially uncover mechanisms of exposure-related disease or negative health outcomes. The purpose of this summary is to serve as an overview of omics methodologies for nurse scientists conducting environmental health research and provides future directions of this work as well as exemplar funding opportunities that demonstrate the growing need and interest in this area. The intersection of nursing and exposure science will accelerate the work in environmental health and bring forth translation of research findings into clinical and community practice. Importantly, this information can better help us understand the variation in response to the environment and support environmental health policy change at the local, state, and federal level to improve community health and well-being.
护士科学家在开展环境卫生研究方面具有理想的优势,认识到组学在环境暴露与个体独特生理机能在人类健康结果中的复杂关系中所起的作用至关重要。重要的是,组学可以为护士科学家提供一种工具,用于测量暴露情况、展示与暴露相关的分子表型变化,并有可能揭示与暴露相关疾病或负面健康结果的机制。本综述的目的是为从事环境卫生研究的护士科学家提供组学方法的概述,并提供这项工作的未来方向以及示例资助机会,以证明该领域日益增长的需求和兴趣。护理与暴露科学的交叉将加速环境卫生方面的工作,并推动研究结果转化为临床和社区实践。重要的是,这些信息可以更好地帮助我们理解对环境反应的差异,并支持地方、州和联邦层面的环境卫生政策变革,以改善社区健康和福祉。