Getaneh Zegeye, Ayelgn Fekadu, Asemahegn Geletaw, Geleta Habtamu, Yalew Aregawi, Melak Tadele
Department of Hematology and Immunohematology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.
School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar Hospital, P.O. Box 196, Gondar, Ethiopia.
BMC Res Notes. 2020 Feb 27;13(1):113. doi: 10.1186/s13104-020-04963-0.
The purpose of this study was comparing the erythrocyte sedimentation rate (ESR) results of trisodium citrate (TSC) and ethylene diamine tetra-acetic acid (EDTA) anticoagulants. A comparative cross-sectional study was conducted at the University of Gondar specialized referral hospital, northwest Ethiopia. A total of 70 TB presumptive participants were recruited. From each of the 70 participants of the study, 3 and 1.6 ml of blood was collected in EDTA tubes and 0.4 ml of trisodium Citrate anticoagulant containing test tubes, respectively.
The mean ± SD values of ESR were 57.9 ± 41.45 mm/h in EDTA and 50.99 ± 43.5 mm/h in TSC anticoagulated blood. The mean difference of ESR values between EDTA and TSC blood (6.91 ± 13.66 mm/h) was statistically significant. The Mean ± SD of ESR values using EDTA and TSC in males were 59.57 ± 42.31 and 53.57 ± 44.61 mm/h while for females it was 54.71 ± 40.44 and 46.04 ± 41.82 mm/h, respectively. The study indicated that there was a significant difference between ESR values with EDTA and TSC anticoagulants.
本研究旨在比较柠檬酸钠（TSC）和乙二胺四乙酸（EDTA）抗凝剂的红细胞沉降率（ESR）结果。在埃塞俄比亚西北部的贡德尔大学专科医院进行了一项比较横断面研究。共招募了70名疑似结核病参与者。在该研究的70名参与者中，分别在EDTA管中采集3ml和1.6ml血液，在含有柠檬酸钠抗凝剂的试管中采集0.4ml血液。
EDTA抗凝血液中ESR的均值±标准差为57.9±41.45mm/h，TSC抗凝血液中为50.99±43.5mm/h。EDTA和TSC血液之间ESR值的平均差异（6.91±13.66mm/h）具有统计学意义。男性使用EDTA和TSC时ESR值的均值±标准差分别为59.57±42.31和53.57±44.61mm/h，女性则分别为54.71±40.44和46.04±41.82mm/h。该研究表明，使用EDTA和TSC抗凝剂时ESR值存在显著差异。
