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New curtachalasin from the sp. DO 1801.

作者信息

Wang Jia, Sang Yining, Tang Siqi, Zhang Peng

机构信息

School of Pharmacy of Tongji Medical College, Huazhong University of Science and Technology, WuHan, China.

出版信息

Nat Prod Res. 2021 Nov;35(21):3701-3706. doi: 10.1080/14786419.2020.1731742. Epub 2020 Feb 27.

DOI:10.1080/14786419.2020.1731742
PMID:32106702
Abstract

One new cytochalasin, named curtachalasin Q (), together with 8 known cytochalasins were isolated from the ethyl acetate extract of the sp. DO1801. The structure of the new compound was elucidated on the basis of IR, UV, HR-ESI-MS, NMR spectra and X-ray diffraction. Compound and were not cytotoxic (IC>50uM) against four tumour cell lines (SW-1990, ASPC-1, HepG2 and Hep3B).

摘要

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