Auker L, Cordingley L, Pye S R, Griffiths C E M, Young H S
Centre for Dermatology Research, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Br J Dermatol. 2020 Dec;183(6):1094-1102. doi: 10.1111/bjd.18979. Epub 2020 Apr 13.
Psoriasis is associated with an increased risk of cardiovascular disease. Despite recommendation that exercise is important for cardiorespiratory fitness, patients with psoriasis avoid participation in physical activities for reasons that are, as yet, unclear.
This study investigated the relationship between psoriasis-specific experiences and self-reported patterns of exercise, hypothesizing that individuals with psoriasis are less likely to engage in physical activity for reasons that are related to their psoriasis.
In total 404 patients with chronic plaque psoriasis were recruited. History, examination and physical activity were assessed for each participant.
Overall, 52·8% (n = 188) of patients with psoriasis aged 18-65 years and 66% (n = 37) of those aged > 65 years engaged in less than the recommended amount of physical activity for cardiorespiratory fitness. As the severity and psychosocial impact of psoriasis increased, the participation in exercise (of all intensities) decreased. There was a significant negative correlation between Psoriasis Area and Severity Index and total activity in women aged 18-65 years (r = -0·19, 95% confidence interval -0·36 to 0; P = 0·04) and a significant negative correlation between physical activity and Dermatology Life Quality Index (DLQI) in all participants (r = -0·11, 95% confidence interval -0·21 to 0; P = 0·04). Individual components of the DLQI identified barriers to physical activity including skin sensitivity and reluctance to participate in leisure activities.
Psoriasis-specific factors - severity, skin sensitivity, clothing choice, participation in social/leisure activities, and treatments - contribute to exercise avoidance and may augment the increased risk of cardiovascular disease in patients with psoriasis.
银屑病与心血管疾病风险增加相关。尽管推荐运动对心肺健康很重要，但银屑病患者却因尚不明确的原因而避免参加体育活动。
本研究调查银屑病特定经历与自我报告的运动模式之间的关系，假设银屑病患者因与银屑病相关的原因而较少参与体育活动。
共招募了404例慢性斑块状银屑病患者。对每位参与者进行病史、检查及体育活动评估。
总体而言，18至65岁的银屑病患者中有52.8%（n = 188），65岁以上的患者中有66%（n = 37）的体育活动量低于心肺健康推荐量。随着银屑病严重程度及社会心理影响的增加，各种强度运动的参与度均下降。在18至65岁女性中，银屑病面积和严重程度指数与总活动量之间存在显著负相关（r = -0.19，95%置信区间 -0.36至0；P = 0.04），且在所有参与者中，体育活动与皮肤病生活质量指数（DLQI）之间存在显著负相关（r = -0.11，95%置信区间 -0.21至0；P = 0.04）。DLQI的各个组成部分均确定了体育活动的障碍，包括皮肤敏感性及不愿参加休闲活动。
银屑病特异性因素——严重程度、皮肤敏感性、着装选择、参与社交/休闲活动及治疗——导致运动回避，并可能加剧银屑病患者心血管疾病风险的增加。
