Ahmad Md Afroz, Mujeeb Mohd, Akhtar Mohd, Khushtar Mohd, Arif Mohd, Haque Md Rafiul
Department of Pharmacy, Integral University, Lucknow, India.
Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India.
Drug Res (Stuttg). 2020 Apr;70(4):123-130. doi: 10.1055/a-1115-4669. Epub 2020 Feb 28.
Herbal medicines therapy is appreciated by many research works because herbal drugs have relatively high therapeutic window, lower side effects and more cost effective. Guggulipid is an ethyl acetate extract of resin known as guggul from the tree . Chemical analysis revealed that the compounds responsible for the major activities of gum guggul are the isomers E- and Z-guggulsterone. Guggul has been used for thousands of years in the treatment of arthritis, inflammation, obesity, cardiac protection, anti-ulcer, anti-epileptic and disorders of lipid metabolism. This review is an assortment of available information reported on its chemical, pharmacological and toxicological properties in various research studies. The available therapeutic properties of guggulipid make it suitable natural product for the treatment of various disorders like inflammation, pain, wounds, liver disorder and Acne etc. Graphical Abstract Graphical Abstract.
草药疗法受到许多研究工作的青睐，因为草药药物具有相对较高的治疗窗、较低的副作用且更具成本效益。古古勒脂是一种从树上提取的名为古古勒的树脂的乙酸乙酯提取物。化学分析表明，负责古古勒树胶主要活性的化合物是E-和Z-古古勒甾酮异构体。古古勒在治疗关节炎、炎症、肥胖、心脏保护、抗溃疡、抗癫痫和脂质代谢紊乱方面已使用了数千年。本综述是对各种研究中报道的有关其化学、药理和毒理学特性的现有信息的汇总。古古勒脂现有的治疗特性使其成为治疗各种疾病如炎症、疼痛、伤口、肝脏疾病和痤疮等的合适天然产物。图形摘要 图形摘要。
