Discipline of Nutrition and Dietetics/Auckland Cancer Society Research Centre, School of Medical Sciences, Faculty of Medicine and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand.
Nutrients. 2020 Feb 26;12(3):609. doi: 10.3390/nu12030609.
(Sw. Karst) is a common bracket fungus, with a woody texture. It is found predominantly in coniferous forests in temperate regions throughout Europe and Asia. has been extensively used for medicinal purposes, particularly in Chinese and Korean traditional medicine. In this mini-review, the anti-cancer characteristics of F. pinicola extracts were investigated. In vitro experiments revealed the pro-apoptotic, anti-oxidant and anti-inflammatory properties of extracts, whilst two of three in vivo studies reported an inhibition of tumour growth and prolonged survival. Only studies wherein fungal specimens were sourced from Europe or Asia were included in this review, as samples sourced as from North America were probably not , but a different species. Although not one of the most revered fungal species, F. pinicola has been used as a medicinal fungus for centuries, as well as consumed as a health food supplement. To date, the results from only three in vivo studies, investigating anti-cancer properties, have been published. Further studies, using comprehensively identified specimens, are required to fully elucidate the anti-cancer properties of F. pinicola extracts.
(Sw. Karst) 是一种常见的木生菌，质地坚硬。它主要分布在欧洲和亚洲的温带针叶林中。长期以来，它一直被广泛用于药用，特别是在中国和韩国的传统医学中。在这个小型综述中，研究了 F. pinicola 提取物的抗癌特性。体外实验显示提取物具有促凋亡、抗氧化和抗炎作用，而三项体内研究中的两项报告了肿瘤生长的抑制和生存时间的延长。本综述仅纳入了真菌标本源自欧洲或亚洲的研究，因为从北美获得的样本可能不是 Sw. Karst，而是其他物种。尽管 F. pinicola 不是最受推崇的真菌物种之一，但它已被用作药用真菌数百年，并被用作保健品食用。迄今为止，仅发表了三项研究抗癌特性的体内研究结果。需要使用经过全面鉴定的标本进行进一步研究，以充分阐明 F. pinicola 提取物的抗癌特性。
