Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
BMC Med. 2020 Mar 4;18(1):45. doi: 10.1186/s12916-020-1512-5.
Spread of malaria and antimalarial resistance through human movement present major threats to current goals to eliminate the disease. Bordering the Greater Mekong Subregion, southeast Bangladesh is a potentially important route of spread to India and beyond, but information on travel patterns in this area are lacking.
Using a standardised short survey tool, 2090 patients with malaria were interviewed at 57 study sites in 2015-2016 about their demographics and travel patterns in the preceding 2 months.
Most travel was in the south of the study region between Cox's Bazar district (coastal region) to forested areas in Bandarban (31% by days and 45% by nights), forming a source-sink route. Less than 1% of travel reported was between the north and south forested areas of the study area. Farmers (21%) and students (19%) were the top two occupations recorded, with 67 and 47% reporting travel to the forest respectively. Males aged 25-49 years accounted for 43% of cases visiting forests but only 24% of the study population. Children did not travel. Women, forest dwellers and farmers did not travel beyond union boundaries. Military personnel travelled the furthest especially to remote forested areas.
The approach demonstrated here provides a framework for identifying key traveller groups and their origins and destinations of travel in combination with knowledge of local epidemiology to inform malaria control and elimination efforts. Working with the NMEP, the findings were used to derive a set of policy recommendations to guide targeting of interventions for elimination.
疟疾的传播和抗疟药物的耐药性通过人类的活动而扩散,这对当前消除疟疾的目标构成了重大威胁。孟加拉国东南部毗邻大湄公河次区域,是向印度及其他地区传播的一个潜在重要途径,但该地区的旅行模式信息却十分缺乏。
2015-2016 年,使用标准化的简短调查工具,在 57 个研究点对 2090 名疟疾病例进行了访谈,询问他们在过去 2 个月中的人口统计学特征和旅行模式。
大多数旅行是在研究区域的南部,从考克斯巴扎尔区(沿海地区)到班达班的森林地区(白天占 31%,夜间占 45%),形成了一个源-汇路线。报告的旅行中,只有不到 1%是在研究区域的北部和南部森林地区之间。农民(21%)和学生(19%)是记录到的前两个职业,分别有 67%和 47%的人前往森林。25-49 岁的男性占前往森林就诊病例的 43%,但仅占研究人群的 24%。儿童没有旅行。女性、森林居民和农民没有越过联盟边界旅行。军人旅行的距离最远,尤其是到偏远的森林地区。
这里展示的方法提供了一个框架,用于结合当地流行病学知识,确定关键旅行者群体及其旅行的来源和目的地,以指导疟疾控制和消除工作。与国家疟疾消除计划合作,研究结果被用于提出一系列政策建议,以指导消除干预措施的针对性。