Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Epidemiology and Biostatistics Department, Neyshabur University of Medical Sciences, Neyshabur, Iran.
BMC Endocr Disord. 2020 Mar 5;20(1):32. doi: 10.1186/s12902-020-0519-4.
The current work examined experiences of Health-Related Quality of Life (HRQOL) among older adults with a diagnosis of Diabetes Mellitus (DM) over time compared to those without a diagnoses DM.
The sample was drawn from six biennial waves of the New Zealand Health, Work and Retirement survey, a prospective population-based cohort study of older adults 55-70 years at baseline. Data on sociodemographic factors, health behaviours, chronic disease diagnoses and physical and mental HRQOL (SF-12v2) were obtained using six biennial surveys administered 2006-2016. Generalised Estimating Equation models, adjusted for time-constant and -varying factors, were employed to compare HRQOL and its determinants over time for older adults with and without a diagnosis of DM.
DM was negatively associated with physical HRQOL [β (95% CI) - 7.43 (- 8.41, - 6.44)] with older adults affected by DM reporting scores 7.4 points lower than those without DM. Similarly, the mean Mental HRQOL score was lower among those affected by DM [β = - 4.97 (- 5.93, - 4.01)] however, scores increased over time for both groups (p < 0.001). Greater age, more chronic conditions, sight and sleep problems, obesity, lower annual income, and fewer years of education were predictors of poorer HRQOL among older adults.
Older adults affected by diabetes experienced poorer physical and mental HRQOL compared to those not affected when controlling for a range of sociodemographic and health related indices. A management aim must be to minimise the gap between two groups, particularly as people age.
本研究旨在考察随着时间的推移，患有糖尿病（DM）的老年人与未患 DM 的老年人在健康相关生活质量（HRQOL）方面的经历。
本研究的样本来自新西兰健康、工作和退休调查的六个两年期波次，这是一项针对 55-70 岁基线老年人的前瞻性基于人群的队列研究。使用六次两年期调查（2006-2016 年）获得了社会人口统计学因素、健康行为、慢性疾病诊断以及身体和心理健康 HRQOL（SF-12v2）的数据。采用广义估计方程模型，根据时间不变和变化因素进行调整，比较了患有和不患有 DM 的老年人随时间变化的 HRQOL 及其决定因素。
DM 与身体 HRQOL 呈负相关[β（95%CI）-7.43（-8.41，-6.44）]，患有 DM 的老年人报告的得分比没有 DM 的老年人低 7.4 分。同样，受 DM 影响的人的平均心理 HRQOL 得分较低[β=-4.97（-5.93，-4.01）]，但两组的得分都随着时间的推移而增加（p<0.001）。年龄较大、患有更多慢性疾病、视力和睡眠问题、肥胖、年收入较低和受教育年限较少是老年人 HRQOL 较差的预测因素。
在控制一系列社会人口统计学和健康相关指标后，患有糖尿病的老年人的身体和心理 HRQOL 比未患病的老年人差。管理目标必须是尽量缩小两组之间的差距，特别是随着人们年龄的增长。
