Leyden Eimear, Hanson Petra, Halder Louise, Rout Lucy, Cherry Ishbel, Shuttlewood Emma, Poole Donna, Loveder Mark, Abraham Jenny, Kyrou Ioannis, Randeva Harpal S, Lam F T, Menon Vinod, Barber Thomas M
Division of Biomedical Sciences, Warwick Medical School, Clinical Sciences Research Laboratories, University Hospitals Coventry and Warwickshire, Coventry, UK.
Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism, University Hospitals Coventry and Warwickshire, Coventry, UK.
Clin Endocrinol (Oxf). 2021 Feb;94(2):204-209. doi: 10.1111/cen.14354. Epub 2020 Nov 6.
Age is sometimes a barrier for acceptance of patients into a hospital-based obesity service. Our aim was to explore the effect of age on the ability to lose weight through lifestyle interventions, implemented within a hospital-based obesity service.
Retrospective study.
We included a cohort of randomly selected patients with morbid obesity (n = 242), who attended our hospital-based obesity service during 2005-2016 and received only lifestyle weight loss interventions.
Primary outcome measures were percentage weight loss (%WL) and percentage reduction in body mass index (%rBMI) following implemented lifestyle interventions. Data were stratified according to patient age at referral: group 1 (age < 60 years, n = 167) and group 2 (age ≥ 60 years, n = 75). Weight loss was compared between groups, and correlations with age at referral were explored.
The duration of hospital-based weight loss interventions ranged between 1 and 143 months (mean: 38.9 months; SD: 32.3). Baseline BMI at referral differed significantly between groups 1 and 2 (49.7 kgm [SD: 8.7] vs 46.9 kgm [SD: 6.1], respectively; P < .05). Following implemented lifestyle interventions, between groups 1 and 2 there were no differences in %WL (6.9% [SD: 16.7] vs 7.3% [SD: 11.60], respectively; P = NS) or %rBMI (8.1% [SD: 14.9] vs 7.8% [SD: 11.7], respectively; p = NS). Overall, there was no significant correlation between patient age at referral and %WL (r = -.13, p = NS).
Older age does not influence the success of weight loss through the implementation of lifestyle modification within a hospital-based obesity service. Therefore, age per se should not influence clinical decisions regarding acceptance of patients to hospital-based obesity services.
年龄有时是患者被纳入医院肥胖服务项目的一个障碍。我们的目的是探讨年龄对通过在医院肥胖服务项目中实施生活方式干预来减肥能力的影响。
回顾性研究。
我们纳入了一组随机选择的病态肥胖患者(n = 242),这些患者在2005年至2016年期间到我们的医院肥胖服务项目就诊,且仅接受了生活方式减肥干预。
主要结局指标是实施生活方式干预后体重减轻百分比(%WL)和体重指数降低百分比(%rBMI)。数据根据转诊时患者年龄分层:第1组(年龄<60岁,n = 167)和第2组(年龄≥60岁,n = 75)。比较两组之间的体重减轻情况,并探讨与转诊时年龄的相关性。
基于医院的减肥干预持续时间在1至143个月之间(平均:38.9个月;标准差:32.3)。第1组和第2组转诊时的基线体重指数有显著差异(分别为49.7 kg/m²[标准差:8.7]和46.9 kg/m²[标准差:6.1];P <.05)。实施生活方式干预后,第1组和第2组在%WL(分别为6.9%[标准差:16.7]和7.3%[标准差:11.60];P =无统计学意义)或%rBMI(分别为8.1%[标准差:14.9]和7.8%[标准差:11.7];p =无统计学意义)方面没有差异。总体而言,转诊时患者年龄与%WL之间没有显著相关性(r = -0.13,p =无统计学意义)。
在医院肥胖服务项目中,年龄较大不会影响通过实施生活方式改变来减肥的成功率。因此,年龄本身不应影响关于患者是否被纳入医院肥胖服务项目的临床决策。