Electrical and Computer Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4K1, Canada.
Anal Chem. 2020 Apr 7;92(7):5532-5539. doi: 10.1021/acs.analchem.0c00402. Epub 2020 Mar 11.
Bisphenol A, an endocrine disrupting compound, is widely used in food and beverage packaging, and it then leaches in food and source water cycles, and thus must be monitored. Here, we report a simple, low-cost and sensitive electrochemical sensor using graphene oxide and β-cyclodextrin functionalized multiwalled carbon nanotubes for the detection of BPA in water. This sensor electrode system combines the high surface area of graphene oxide and carbon nanotubes, and the superior host-guest interaction capability of β-cyclodextrin. A diffusion-controlled oxidation reaction involving equal numbers of protons and electrons facilitated the electrochemical sensing of BPA. The sensor showed a two-step linear response from 0.05 to 5 μM and 5-30 μM with a limit of detection of 6 nM. The sensors also exhibited a reproducible and stable response over one month with negligible interference from common inorganic and organic species, and an excellent recovery with real water samples. The proposed electrochemical sensor can be promising for the development of simple low-cost water quality monitoring system for monitoring of BPA in water.
双酚 A 是一种内分泌干扰化合物，广泛应用于食品和饮料包装，它会渗出到食物和水源循环中，因此必须进行监测。在这里，我们报告了一种简单、低成本和敏感的电化学传感器，该传感器使用氧化石墨烯和 β-环糊精功能化多壁碳纳米管来检测水中的 BPA。该传感器电极系统结合了氧化石墨烯和碳纳米管的高表面积，以及 β-环糊精的优越主客体相互作用能力。涉及等摩尔质子和电子的扩散控制氧化反应促进了 BPA 的电化学传感。该传感器在 0.05 至 5 μM 和 5-30 μM 范围内呈现出两步线性响应，检测限低至 6 nM。该传感器在一个月内表现出可重复且稳定的响应，对常见的无机和有机物质几乎没有干扰，并且对实际水样具有良好的回收率。该电化学传感器有望开发出用于监测水中 BPA 的简单、低成本水质监测系统。
