Tao Huan, Xie Feiling, Li Zhi, Qu Liangzhuo, Zha Qingbing, Zhu Mingshan
Department of Clinical Laboratory Medical, The First Affiliated Hospital of Jinan University Guangzhou 510630 China.
Department of Medical Laboratory, The Fifth Affiliated Hospital of Jinan University (Heyuan Shenhe People's Hospital) Heyuan 517000 China
RSC Adv. 2025 Jul 22;15(32):26039-26047. doi: 10.1039/d5ra03944d. eCollection 2025 Jul 21.
The gradual emissions of bisphenol A (BPA) pose significant health risks by interfering with hormonal regulation, which urgently require to develop an efficient and rapid detection method. Here, an electrochemical sensor using graphene oxide anchored ferric vanadate acid (GO/FeVO) nanocomposite was developed for BPA detection. The electrochemical signals of GO grafted on FeVO was significantly enhanced by 7.4-fold relative to that of pure FeVO, attributed to transition metal valence effects and adsorption by H-bond. The optimized system achieved a detection limit of 1.18 μM with a linear range of 0.01-40 μM. Additionally, it displayed outstanding stability, reproducibility and selectivity. These findings demonstrate strong potential for environmental monitoring and clinical diagnostics, particularly for rapid on-site BPA detection in tap water and urine. The sensor of GO/FeVO with high conductivity and catalytic activity offers a sensitive, cost-effective solution for BPA detection in environmental and medical clinics.
双酚A（BPA）的逐渐释放通过干扰激素调节对健康构成重大风险，这迫切需要开发一种高效快速的检测方法。在此，开发了一种使用氧化石墨烯锚定钒酸铁（GO/FeVO）纳米复合材料的电化学传感器用于检测BPA。相对于纯FeVO，接枝在FeVO上的GO的电化学信号显著增强了7.4倍，这归因于过渡金属价态效应和氢键吸附。优化后的系统检测限为1.18 μM，线性范围为0.01 - 40 μM。此外，它还表现出出色的稳定性、重现性和选择性。这些发现表明该传感器在环境监测和临床诊断方面具有巨大潜力，特别是用于自来水和尿液中BPA的快速现场检测。具有高导电性和催化活性的GO/FeVO传感器为环境和医疗诊所中的BPA检测提供了一种灵敏且经济高效的解决方案。
