纳米技术在药物靶向中的战略应用及其对人类健康的影响：聚焦综述
Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review.
作者信息
Maurya Anand, Singh Anurag Kumar, Mishra Gaurav, Kumari Komal, Rai Arati, Sharma Bhupesh, Kulkarni Giriraj T, Awasthi Rajendra
机构信息
Faculty of Ayurveda, Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
出版信息
Interv Med Appl Sci. 2019 Mar;11(1):38-54. doi: 10.1556/1646.11.2019.04.
Since the development of first lipid-based nanocarrier system, about 15% of the present pharmaceutical market uses nanomedicines to achieve medical benefits. Nanotechnology is an advanced area to meliorate the delivery of compounds for improved medical diagnosis and curing disease. Nanomedicines are gaining significant interest due to the ultra small size and large surface area to mass ratio. In this review, we discuss the potential of nanotechnology in delivering of active moieties for the disease therapy including their toxicity evidences. This communication will help the formulation scientists in understanding and exploring the new aspects of nanotechnology in the field of nanomedicine.
自从首个基于脂质的纳米载体系统问世以来，目前约15%的医药市场使用纳米药物来实现医疗效益。纳米技术是一个先进领域，可改善化合物的递送，以改进医学诊断和治疗疾病。由于尺寸超小且质量比表面积大，纳米药物正引起人们极大的兴趣。在本综述中，我们讨论了纳米技术在递送活性部分用于疾病治疗方面的潜力，包括其毒性证据。本交流将有助于制剂科学家理解和探索纳米技术在纳米医学领域的新方面。
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