Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman.
Institute for Clinical Medicine, Faculty of Health Science, University of Aarhus, Denmark.
Curr Opin Pulm Med. 2020 May;26(3):197-202. doi: 10.1097/MCP.0000000000000675.
Mass gathering events bring people from across all continents increasing the risk of spread of aerosol transmissible respiratory tract infections. Respiratory tract infections for instance in pilgrims attending the world's largest recurring annual pilgrimage, the Hajj are common. We review recent literature on viral and bacterial infectious diseases with special focus on the Hajj.
The prevalence of bacterial and viral infections continue to increase, because of the acquisition of rhinovirus, coronaviruses (229E, HKU1, OC43), influenza A H1N1, Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus during Hajj. Whilst MERS-CoV continues to circulate in the Middle East, no cases of MERS-CoV have yet been identified in pilgrims during Hajj.
Respiratory tract infections are a major cause of morbidity in pilgrims attending mass gathering events. The management of severe respiratory infections should consider investigation and empirical coverage for the most likely agents based on syndromic surveillance data from hosting country and /or other relevant exposure history during events. Pneumococcal and Pertussis vaccines should be recommended for Hajj pilgrims.
人群大规模聚集会增加传染性呼吸道气溶胶传播感染的风险,来自各大洲的人群都汇集在一起。例如,参加世界上最大的年度朝觐活动——麦加朝圣的朝圣者中,呼吸道感染很常见。我们综述了最近关于病毒性和细菌性传染病的文献,特别关注了朝觐期间的这些疾病。
由于在朝圣期间感染了鼻病毒、冠状病毒(229E、HKU1、OC43)、甲型流感 H1N1、肺炎链球菌、流感嗜血杆菌和金黄色葡萄球菌,细菌性和病毒性感染的患病率继续上升。虽然中东地区仍有中东呼吸综合征冠状病毒(MERS-CoV)传播,但在朝圣者中尚未发现 MERS-CoV 病例。
呼吸道感染是参加大规模集会活动的朝圣者发病的主要原因。严重呼吸道感染的治疗应根据宿主国家的综合征监测数据和/或事件期间的其他相关暴露史,考虑对最可能的病原体进行调查和经验性覆盖。应建议接种流感嗜血杆菌疫苗和百白破疫苗。