From the Department of Nuclear Medicine & Minnan PET Center.
Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.
Clin Nucl Med. 2020 Jun;45(6):468-470. doi: 10.1097/RLU.0000000000003000.
A 71-year-old man with pathologically confirmed rectal cancer underwent F-FDG PET/CT before radical operation, which showed multiple nodules with low uptake in bilateral pleura and 1 solitary pulmonary nodule with slight uptake in left lung. The subpleural nodule was diagnosed as benign lesion through the biopsy. Ga-labeled fibroblast-activation-protein inhibitor PET/CT was performed for further evaluation, which showed low uptake in bilateral subpleural nodules but focally increased uptake in the nodule of left lung. This nodule was found to be a primary lung adenocarcinoma by the CT-guided biopsy. A diagnosis of rectum and lung double primary malignancies was finally made.
一位 71 岁男性，经病理证实患有直肠癌，在根治性手术前进行了 F-FDG PET/CT 检查，结果显示双侧胸膜多个小结节摄取低，左肺单发小结节摄取轻度增加。通过活检，胸膜下结节被诊断为良性病变。为进一步评估，进行了 Ga 标记的成纤维细胞激活蛋白抑制剂 PET/CT 检查，结果显示双侧胸膜下小结节摄取低，但左肺结节局灶性摄取增加。经 CT 引导下活检，该结节被发现为原发性肺腺癌。最终诊断为直肠和肺双原发恶性肿瘤。
