经颅磁刺激对孤独症谱系障碍儿童β节律的影响。一项脑磁图研究。
The Effect of pT-TMS on Beta Rhythm in Children with Autism Disorder. A MEG Study.
作者信息
Anninos Photios, Chatzimichael Athanasios, Anninou Nicolia, Kotini Athanasia, Adamopoulos Adam, Gemousakakis Triandafillos, Tsagas Nicolaos
机构信息
Laboratory of Medical Physics, Department of Medicine, School of Health Sciences, Democritus University of Thrace, University Campus, Alexandroupoli, Greece.
Department of Paediatrics, University Hospital of Alexandroupoli, Democritus University of Thrace, University Campus, Alexandroupoli, Greece.
出版信息
Maedica (Bucur). 2019 Dec;14(4):332-342. doi: 10.26574/maedica.2019.14.4.332.
We investigated the beta rhythm in 10 children with autism disorders (six boys and four girls) aged 5-12 (mean± SD: 8.3± 2.1) before and after the application of pico Tesla transcranial magnetic stimulation (pT-TMS) using magnetoencephalography (MEG). The MEG was car-ried out in a magnetically shielded room with a whole-head 122-channel gradiometer. After applying pT-TMS, we observed a beta rhythm increase towards the frequency range of 18-26 Hz in seven out of 10 patients (70%). We created a score that rated the level of improvement for each patient: 1=some change; 2=minor change; and 3=major change. All patients had an improvement in their clinical symptoms after the application of pT-TMS. There was a correlation between the clinical score and the increase of channels in the frequency range 18-26 Hz after pT-TMS. We concluded that the application of pT-TMS affected the beta rhythm in children with autism disorder. Therefore, more studies need to be further conducted.
我们使用脑磁图（MEG）研究了10名年龄在5至12岁（平均±标准差：8.3±2.1）的自闭症谱系障碍儿童（6名男孩和4名女孩）在应用皮特斯拉经颅磁刺激（pT-TMS）前后的β节律。MEG在配备全头122通道梯度仪的磁屏蔽室内进行。应用pT-TMS后，我们观察到10名患者中有7名（70%）的β节律向18至26赫兹的频率范围增加。我们创建了一个评分来评估每位患者的改善程度：1 = 有一些变化；2 = 有轻微变化；3 = 有显著变化。应用pT-TMS后，所有患者的临床症状均有改善。临床评分与pT-TMS后18至26赫兹频率范围内通道的增加之间存在相关性。我们得出结论，pT-TMS的应用影响了自闭症谱系障碍儿童的β节律。因此，需要进一步开展更多研究。
Zotero 插件