Clinical Pharmacy Unit, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Social Pharmacy Unit, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
BMC Cardiovasc Disord. 2020 Mar 11;20(1):129. doi: 10.1186/s12872-020-01414-3.
Uncontrolled hypertension is one of the major risk factors of cardiovascular and cerebrovascular diseases. The prevalence of hypertension in Ethiopia is expected to reach up to 30%. The aim of this study was to determine the prevalence of uncontrolled hypertension among hypertensive patients on treatment in Ethiopia.
Electronic databases and search engines including EMBASE (Ovid), PubMed/Medline, and Google Scholar were searched for original records in the English language addressing hypertension control in Ethiopia from 2000 to 2018. Data were extracted using a format prepared in Microsoft Excel and exported to STATA 15.0 software for analyses. The study protocol is registered at PROSPERO with reference number ID: CRD42018116336.
A total of 13 studies with 5226 hypertension patients were included for systematic review and meta-analysis. The pooled prevalence of uncontrolled hypertension in Ethiopia was 48% (95% confidence interval (CI): 36, 61%). The result of the sub-group analysis, based on the year of publications, revealed that the prevalence of uncontrolled BP was highest in 2016 (63%; CI: 60, 67%) and in 2015 (59%; CI: 53, 65%). Univariate meta-regression revealed that sampling distribution was not a source of heterogeneity for the pooled estimate as well as the sub group analysis.
The prevalence of uncontrolled hypertension was high in Ethiopia. This alarming public health issue fuels the ever-increasing cardiovascular and cerebrovascular diseases. The ministry of health has to design a policy and implementation mechanisms to reduce uncontrolled hypertension prevalence and improve awareness on blood pressure control.
未得到控制的高血压是心血管和脑血管疾病的主要危险因素之一。预计埃塞俄比亚的高血压患病率将达到 30%。本研究旨在确定在埃塞俄比亚接受治疗的高血压患者中未得到控制的高血压的患病率。
电子数据库和搜索引擎（包括 Ovid 版 EMBASE、PubMed/Medline 和 Google Scholar）对 2000 年至 2018 年期间用英语发表的有关埃塞俄比亚高血压控制的原始文献进行了检索。使用 Microsoft Excel 中准备的格式提取数据，并将其导出到 STATA 15.0 软件进行分析。该研究方案在 PROSPERO 注册，参考编号为 ID：CRD42018116336。
共有 13 项研究纳入了 5226 名高血压患者进行系统评价和荟萃分析。埃塞俄比亚未得到控制的高血压的总患病率为 48%（95%置信区间（CI）：36,61%）。根据发表年份的亚组分析结果表明，未得到控制的血压患病率在 2016 年最高（63%；CI：60,67%），2015 年其次（59%；CI：53,65%）。单变量 Meta 回归显示，抽样分布不是汇总估计值以及亚组分析的异质性来源。
埃塞俄比亚未得到控制的高血压患病率较高。这一令人震惊的公共卫生问题加剧了心血管和脑血管疾病的不断增加。卫生部必须制定政策和实施机制，以降低未得到控制的高血压患病率，并提高对血压控制的认识。
