Li J Y, Mai W, Tan H Q, Jian M T, Deng H, Chen Z P, Chen H H
Division of Infectious Disease Control and Prevention, Guangdong Provincial Zhaoqing City Center for Disease Control and Prevention, Zhaoqing 526060, China.
Division of Microbiological Inspection,Guangdong Provincial Zhaoqing City Center for Disease Control and Prevention, Zhaoqing 526060, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Feb 10;41(2):226-230. doi: 10.3760/cma.j.issn.0254-6450.2020.02.016.
To investigate the epidemiological characteristics and clinic symptoms of an outbreak of infectious diarrhea caused by Sapovirus, in CT community, Zhaoqing, Guangdong province. Retrospective study of field epidemiology investigation was carried out and Chi-square test was used enteroviruses were detected by RT-PCR in swab, fecal specimens and water samples. A total of 422 cases were identified in this outbreak, with the prevalence as 11.95. Cases mainly concentrated between 21 and 24, December, with curves noticed by point- source and peaked on the 22(nd). Symptoms mainly appeared as vomiting, with watery stool. Patients were founded in every village, with the highest prevalence appeared in the elderly (25.20) but involved in every age group. Sapovirus infection was most frequently seen in the population under 25 years of age, with overall prevalence as 16.41. People older than 50 years of age took the second place (12.05), and the lowest was seen between 25 to 49 years age group (8.42). Sapovirus was detected in both swab and fecal specimens, with the positive rate as 38.78. Both general and heat- resistant coliformed-bacteria were detected in the 24 monitored water samples, with the qualification rates as 95.83, 45.83 and 50.00, respectively. However, Sapovirus was not detected in any of the water samples. Our findings confirmed that an outbreak, caused by sapovirus infection in CT community was most likely related to the central water supply. The surveillance system for infectious diarrheal diseases should be improved and both public health awareness and surveillance programs on drinking water should be strengthened.
为调查广东省肇庆市CT社区由札幌病毒引起的感染性腹泻暴发的流行病学特征及临床症状，开展现场流行病学调查回顾性研究，并采用卡方检验。通过逆转录聚合酶链反应（RT-PCR）检测拭子、粪便标本和水样中的肠道病毒。本次暴发共确诊422例病例，患病率为11.95。病例主要集中在12月21日至24日，呈点源曲线，于22日达到高峰。症状主要表现为呕吐和水样便。各村均有患者，患病率最高的是老年人（25.20），但各年龄组均有涉及。札幌病毒感染在25岁以下人群中最为常见，总体患病率为16.41。50岁以上人群次之（12.05），25至49岁年龄组最低（8.42）。在拭子和粪便标本中均检测到札幌病毒，阳性率为38.78。在24份监测水样中均检测到总大肠菌群和耐热大肠菌群，合格率分别为95.83、45.83和50.00。然而，在任何一份水样中均未检测到札幌病毒。我们的研究结果证实，CT社区由札幌病毒感染引起的暴发很可能与集中供水有关。应完善感染性腹泻疾病监测系统，加强公众卫生意识及饮用水监测项目。
