Department of Neurological Surgery, Göttingen University Hospital, Robert-Koch-Str. 40, 37075, Göttingen, Germany.
Neurosurg Rev. 2021 Apr;44(2):987-993. doi: 10.1007/s10143-020-01246-x. Epub 2020 Mar 12.
To evaluate if the unruptured intracranial aneurysm treatment score (UIATS) is a sensitive tool to detect aneurysms at risk of rupture, we conducted an a posteriori retrospective study on ruptured intracranial aneurysms. We performed a retrospective analysis of adult patients admitted to our center from January 2010 to April 2016 with aneurysmal subarachnoid hemorrhage. The UIATS was applied to all ruptured aneurysms. Patients for whom the UIATS recommended treatment were labeled as "true positives," whereas patients for whom the UIATS recommended observation were labeled as "false negatives." Patients for whom the UIATS was inconclusive were excluded from the final analysis. Based on the UIATS recommendation, a sensitivity analysis was performed. A total of 262 patients with aneurysmal subarachnoid hemorrhage were screened. Of these, 212 were included in our analysis. Median age was 53 years (23-90). Most patients were females (n = 134, 63%), with an equal distribution between low-grade and high-grade hemorrhages (Hunt & Hess ≥ 3 n = 107, 50%). UIATS recommended treatment in n = 52, 25% cases (TP), was inconclusive in n = 93, 44% (excluded), and recommended observation in n = 67, 32% (FN). Based on these data, the UIATS showed a sensitivity of 44% (CI 35-53%). The UIATS exhibits rather low sensitivity for detecting aneurysms at risk of rupture.
为了评估未破裂颅内动脉瘤治疗评分（UIATS）是否是一种检测破裂颅内动脉瘤风险的敏感工具，我们对破裂颅内动脉瘤进行了一项回顾性的、事后的研究。我们对 2010 年 1 月至 2016 年 4 月期间因蛛网膜下腔出血而入住我们中心的成年患者进行了回顾性分析。对所有破裂的动脉瘤都应用了 UIATS。对 UIATS 建议治疗的患者标记为“真阳性”，而对 UIATS 建议观察的患者标记为“假阴性”。对 UIATS 不确定的患者排除在最终分析之外。根据 UIATS 的建议进行了敏感性分析。共筛选出 262 例蛛网膜下腔出血患者，其中 212 例纳入本分析。中位年龄为 53 岁（23-90 岁）。大多数患者为女性（n=134，63%），低分级和高分级出血之间分布均衡（Hunt & Hess ≥3 n=107，50%）。UIATS 建议治疗 n=52 例（25%），建议观察 n=67 例（32%），不确定 n=93 例（44%）。基于这些数据，UIATS 的敏感性为 44%（CI 35-53%）。UIATS 检测破裂风险动脉瘤的敏感性较低。
