青少年 1 型糖尿病患者的睡眠与血糖
Sleep and Glycemia in Youth With Type 1 Diabetes.
出版信息
J Pediatr Health Care. 2020 Jul-Aug;34(4):315-324. doi: 10.1016/j.pedhc.2019.12.002. Epub 2020 Mar 11.
INTRODUCTION
Short sleep duration and quality are problems for many youth, and are associated with difficulties in executive function. Our purpose was to describe subjective and objective sleep characteristics and their associations with executive function, stress and coping, adjustment, and self-management in youth with type 1 diabetes (T1D).
METHOD
Youth with T1D (N = 40; mean age, 13.4 ± 1.9 years; 60% female; 77.1% non-Hispanic white; diabetes duration, 7.1 ± 4.6 years; and hemoglobin A1c, 8.2 ± 1.2%) wore an actigraph and a continuous glucose monitor for 3-7 days and completed questionnaires. Descriptive and bivariate analyses were conducted.
RESULTS
Sleep variability was associated with stress and depressive symptoms, as well as more glucose variability. Consistent rest-activity rhythm timing was associated with fewer trait anxiety symptoms. Robust rhythms were associated with better diabetes self-management.
DISCUSSION
Providers should routinely assess sleep habits in youth, especially those with T1D. Improving consistency in sleep timing and sleep duration may be a potential therapeutic target to improve diabetes clinical outcomes.
简介
睡眠时长过短和睡眠质量不佳是许多年轻人面临的问题，且与执行功能障碍有关。我们的目的是描述青少年 1 型糖尿病（T1D）患者的主观和客观睡眠特征及其与执行功能、压力与应对、适应和自我管理之间的关联。
方法
研究纳入了 40 名 T1D 青少年（平均年龄 13.4±1.9 岁；60%为女性；77.1%为非西班牙裔白人；糖尿病病程为 7.1±4.6 年；糖化血红蛋白为 8.2±1.2%），他们佩戴活动记录仪和连续血糖监测仪 3-7 天，并完成问卷调查。研究进行了描述性和双变量分析。
结果
睡眠变异性与压力和抑郁症状以及更多的血糖变异性相关，而一致的休息-活动节律定时与较少的特质焦虑症状相关。稳定的节律与更好的糖尿病自我管理相关。
讨论
医疗服务提供者应常规评估青少年的睡眠习惯，尤其是 T1D 患者。改善睡眠定时和睡眠时长的一致性可能是改善糖尿病临床结局的潜在治疗靶点。
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