秀丽锦龟对培氟沙星的N-氧化、N-去甲基化及排泄作用
N-oxidation, N-demethylation, and excretion of pefloxacin by the turtle Pseudemys scripta elegans.
作者信息
Vree T B, Vree J B, Baars I M, Hekster Y A, Nouws J F
机构信息
Department of Clinical Pharmacy, Sint Radboud hospital, Nijmegen, The Netherlands.
出版信息
Vet Q. 1988 Oct;10(4):277-80. doi: 10.1080/01652176.1988.9694186.
PMID:3218071
Abstract
Pefloxacin is minimally absorbed by the gastrointestinal tract of the turtle Pseudemys scripta elegans and then N-oxidised and N-demethylated. Pefloxacin is excreted within one hour after being given orally to the turtles.
摘要
培氟沙星在秀丽锦龟的胃肠道中吸收极少，然后进行N - 氧化和N - 去甲基化。给乌龟口服培氟沙星后，它会在一小时内排出。
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