Food and Agriculture Organization of the United Nations (FAO), Viale delle Terme di Caracalla, 00153 Rome, Italy.
The Pirbright Institute, Ash Road, Surrey GU24 0NF, UK.
Viruses. 2020 Mar 15;12(3):313. doi: 10.3390/v12030313.
Peste des Petits Ruminants (PPR) is a highly contagious viral disease of both domestic (goats and sheep) and wild ruminants. Caused by a morbillivirus, that belongs to the family Paramyxoviridae. The disease is clinically and pathologically similar to rinderpest of cattle and human measles. PPR is one of the most economically devastating viral diseases of small ruminants. In April 2015, the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE) launched the PPR Global Control and Eradication Strategy (PPR GCES) with the vision for global eradication by 2030. There is a strong and lasting international consensus to eradicate the disease in order to protect the livelihoods of the world's poorest populations. As with any disease, eradication is feasible when, policy, scientific and technical challenges are addressed. Ten majors challenges are described in this paper namely: understanding small ruminant production, facilitating research to support eradication, refining laboratory testing, improving epidemiological understanding of the virus, defining infection of wildlife and other species, optimizing vaccine delivery and novel vaccines, developing better control of animal movement, heightening serological monitoring, understanding socio-economic impact, and garnering funding and political will.
小反刍兽疫（PPR）是一种高度接触性传染病，可感染家（山羊和绵羊）养和野生反刍动物。它由副黏病毒科麻疹病毒属的一种病毒引起。该疾病在临床上和病理学上与牛瘟和人类麻疹相似。小反刍兽疫是小反刍动物中最具破坏性的病毒性疾病之一。2015 年 4 月，联合国粮食及农业组织（FAO）和世界动物卫生组织（OIE）启动了小反刍兽疫全球控制和消灭战略（PPR GCES），目标是到 2030 年在全球消灭该疾病。为了保护世界上最贫困人口的生计，国际社会强烈而持久地达成了消灭该疾病的共识。与任何疾病一样，只要解决了政策、科学和技术方面的挑战，消灭疾病就具有可行性。本文描述了十大主要挑战，包括：了解小反刍动物生产情况、促进支持消灭工作的研究、完善实验室检测、提高对病毒流行情况的认识、确定野生动物和其他物种的感染情况、优化疫苗接种和新型疫苗、改进动物移动控制、加强血清学监测、了解社会经济影响、以及筹集资金和政治意愿。
