Collazzoni Alberto, Stratta Paolo, Pacitti Francesca, Rossi Alessandro, Santarelli Valeria, Bustini Massimiliano, Talevi Dalila, Socci Valentina, Rossi Rodolfo
Department of Biotechnological and Applied Clinical Sciences (DISCAB), University of L'Aquila, L'Aquila, Italy.
Department of Mental Health, ASL 1, L'Aquila, Italy.
Front Psychiatry. 2020 Feb 28;11:10. doi: 10.3389/fpsyt.2020.00010. eCollection 2020.
Several studies investigated the role of resilience as a mediating factor for psychopathological phenotypes. The aim of the current study is to explore the putative role of resilience as a mediator between different vulnerability factors and depressive symptoms. One hundred and fifty patients with a major depressive disorder diagnosis have been evaluated on the basis of humiliation (Humiliation Inventory), adverse past family experiences (Risky Family Questionnaire), hopelessness (Beck Hopelessness Scale), and resilience (Resilience Scale for Adult) scores. A multiple regression analysis and a bootstrapping method were carried out to assess the hypothesis that resilience could mediate the relationships between these risk factors as predictors and hopelessness as a dependent variable. Our results show that resilience has a mediating role in the relationship between several risk factors that are specifically involved in interpersonal functioning and hopelessness. The main limitations of the study are the cross-sectional nature of the study, the use of self-report instruments, the lack of personality assessment, and the consideration of the resilience as a unique construct. The understanding of the mechanisms through which resilience mediates the effects of different interpersonal risk factors is crucial in the study of depression. In fact, future prevention-oriented studies can also be carried out considering the mediating role of resilience between interpersonal risk factors and depressive symptoms.
多项研究调查了心理韧性作为心理病理表型中介因素的作用。本研究的目的是探讨心理韧性作为不同脆弱因素与抑郁症状之间中介的假定作用。对150名被诊断为重度抑郁症的患者，根据羞辱感（羞辱感量表）、过去不良家庭经历（风险家庭问卷）、绝望感（贝克绝望量表）和心理韧性（成人心理韧性量表）得分进行了评估。进行了多元回归分析和自抽样法，以评估心理韧性可作为预测因素的这些风险因素与作为因变量的绝望感之间关系的中介这一假设。我们的结果表明，心理韧性在人际功能中特别涉及的几个风险因素与绝望感之间的关系中起中介作用。该研究的主要局限性在于研究的横断面性质、自我报告工具的使用、缺乏人格评估以及将心理韧性视为单一结构。在抑郁症研究中，理解心理韧性介导不同人际风险因素影响的机制至关重要。事实上，未来以预防为导向的研究也可以考虑心理韧性在人际风险因素和抑郁症状之间的中介作用来开展。
