新型快速检测碳青霉烯酶检测方法
Novel Rapid Test for Detecting Carbapenemase.
出版信息
Emerg Infect Dis. 2020 Apr;26(4):793-795. doi: 10.3201/eid2604.181655.
Abstract
We developed a carbapenemase test based on the ability of imipenem to inhibit noncarbapenemase β-lactamases. The test uses bacterial isolates with a fluorescent β-lactamase substrate, producing objective results with 100% sensitivity and specificity in 10 minutes. The assay is inexpensive and consists of only 1 mixing step.
摘要
我们开发了一种基于亚胺培南抑制非碳青霉烯类β-内酰胺酶能力的碳青霉烯酶检测方法。该检测方法使用带有荧光β-内酰胺酶底物的细菌分离株，可在 10 分钟内产生 100%灵敏度和特异性的客观结果。该检测方法成本低廉，仅包含 1 个混合步骤。
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