Ezaki Taisuke, Akatsuka Seiya, Sanjo Tansei, Masuda Takeshi
Department of Urology, Saitama City Hospital, Saitama, Japan.
Division of Pathology, Department of Central Laboratory, Saitama City Hospital, Saitama, Japan.
Case Rep Urol. 2020 Mar 3;2020:6045328. doi: 10.1155/2020/6045328. eCollection 2020.
IgG4-related disease is a systemic fibroinflammatory disorder that occasionally affects the prostate. It is usually considered that patients with IgG4-related disease are at high risk of developing malignancies. A 71-year-old man presented to our hospital with a chief complaint of urinary retention. Prostate biopsy revealed concomitant IgG4-related prostatitis and prostate cancer. IgG4-related prostatitis was a possible cause of urinary retention, and the aggressive nature of prostate cancer was the cause of the patient's death 2 years after diagnosis. This is the fourth case report of prostate cancer accompanied by IgG4-related prostatitis; however, there have been no reports of the two diseases coexisting with high clinical significance. Our case report indicates that patients diagnosed with IgG4-related prostatitis should be carefully followed up considering the risk of prostate cancer.
IgG4相关性疾病是一种系统性纤维炎性疾病，偶尔会累及前列腺。通常认为，IgG4相关性疾病患者发生恶性肿瘤的风险较高。一名71岁男性因尿潴留为主诉前来我院就诊。前列腺活检显示合并IgG4相关性前列腺炎和前列腺癌。IgG4相关性前列腺炎可能是尿潴留的原因，而前列腺癌的侵袭性是患者诊断后2年死亡的原因。这是第四例伴有IgG4相关性前列腺炎的前列腺癌病例报告；然而，尚无关于这两种疾病具有高临床意义共存的报道。我们的病例报告表明，考虑到前列腺癌的风险，对诊断为IgG4相关性前列腺炎的患者应进行仔细随访。
