School of Life and Basic Sciences, Department of Chemistry, SIILAS CAMPUS, Jaipur National University, Jaipur, Rajasthan, 302017, India.
Department of Botany, Aligarh Muslim University, Aligarh, U. P., 202 002, India.
Bioprocess Biosyst Eng. 2020 Aug;43(8):1339-1357. doi: 10.1007/s00449-020-02330-8. Epub 2020 Mar 19.
The development of nanoparticle-based drugs has provided many opportunities to diagnose, treat and cure challenging diseases. Through the manipulation of size, morphology, surface modification, surface characteristics, and materials used, a variety of nanostructures can be developed into smart systems, encasing therapeutic and imaging agents with stealth properties. These nanostructures can deliver drugs to specific tissues or sites and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug-related toxicity and increases the patient's compliance with less frequent dosing. Nanotechnology employing nanostructures as a tool has provided advances in the diagnostic testing of diseases and cure. This technology has proven beneficial in the treatment of cancer, AIDS, and many other diseases. This review article highlights the recent advances in nanostructures and nanotechnology for drug delivery, nanomedicine and cures.
基于纳米粒子的药物的发展为诊断、治疗和治愈具有挑战性的疾病提供了许多机会。通过对尺寸、形态、表面修饰、表面特性和所用材料的操纵，可以将各种纳米结构开发成智能系统，用隐形特性封装治疗和成像剂。这些纳米结构可以将药物递送到特定的组织或部位，并提供控制释放治疗。这种靶向和持续的药物递送可以降低与药物相关的毒性，并提高患者的依从性，减少频繁的给药。纳米技术将纳米结构作为工具，在疾病诊断和治疗方面取得了进展。这项技术已被证明在治疗癌症、艾滋病和许多其他疾病方面是有益的。本文综述了纳米结构和纳米技术在药物输送、纳米医学和治疗方面的最新进展。
