State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, College of Plant Protection, Hunan Agricultural University, Changsha 410128, China.
Annu Rev Plant Biol. 2020 Apr 29;71:575-603. doi: 10.1146/annurev-arplant-010720-022215. Epub 2020 Mar 20.
Plant diseases reduce crop yields and threaten global food security, making the selection of disease-resistant cultivars a major goal of crop breeding. Broad-spectrum resistance (BSR) is a desirable trait because it confers resistance against more than one pathogen species or against the majority of races or strains of the same pathogen. Many BSR genes have been cloned in plants and have been found to encode pattern recognition receptors, nucleotide-binding and leucine-rich repeat receptors, and defense-signaling and pathogenesis-related proteins. In addition, the BSR genes that underlie quantitative trait loci, loss of susceptibility and nonhost resistance have been characterized. Here, we comprehensively review the advances made in the identification and characterization of BSR genes in various species and examine their application in crop breeding. We also discuss the challenges and their solutions for the use of BSR genes in the breeding of disease-resistant crops.
植物病害降低作物产量，威胁全球粮食安全，因此选择抗病品种是作物培育的主要目标。广谱抗性（BSR）是一种理想的特性，因为它可以抵抗一种以上的病原体物种，或抵抗同一病原体的大多数菌株或品系。许多植物中的 BSR 基因已被克隆，并被发现编码模式识别受体、核苷酸结合和富含亮氨酸重复受体以及防御信号和与发病相关的蛋白质。此外，还对数量性状位点、易感性丧失和非寄主抗性背后的 BSR 基因进行了特征描述。在这里，我们全面回顾了在不同物种中鉴定和表征 BSR 基因的进展，并研究了它们在作物培育中的应用。我们还讨论了在培育抗病作物中使用 BSR 基因的挑战及其解决方案。
