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血清维生素D水平与异位妊娠的关系:一项病例对照研究。

Relationship Between Serum Vitamin D Level and Ectopic Pregnancy: A Case-Control Study.

作者信息

Sahhaf Farnaz, Saiyar-Sarai Somaiyeh, Piri Reza, Mohammadi Sahar, Naghavi-Behzad Mohammad

机构信息

Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Family Reprod Health. 2019 Sep;13(3):167-172.

PMID:32201492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7072032/
Abstract

To compare the difference in Vitamin D level between women with ectopic pregnancy and control group. In the present case-control study, 150 patients with ectopic pregnancy were included as case group and 150 women with normal pregnancy as a control group. Then, serum vitamin D levels were measured in both groups and they were then compared with each other. P less than 0.05 was considered statistically significant. The mean age in ectopic pregnancy group was 28.12 ± 5.91 and 27.35 ± 6.21 years old in control group; the difference between two groups was not statistically significant (p = 0.43). The vitamin D level in control group was higher than that of ectopic pregnancy group (p = 0.002). Of all patients, 182 patients (60.66%) had vitamin D deficiency and 64 patients (21.33%) had vitamin D insufficiency. Serum vitamin D level among patients with ectopic pregnancy was statistically lower than women with normal pregnancy.

摘要

比较异位妊娠女性与对照组之间维生素D水平的差异。在本病例对照研究中,纳入150例异位妊娠患者作为病例组,150例正常妊娠女性作为对照组。然后,测量两组的血清维生素D水平并进行相互比较。P值小于0.05被认为具有统计学意义。异位妊娠组的平均年龄为28.12±5.91岁,对照组为27.35±6.21岁;两组之间的差异无统计学意义(p = 0.43)。对照组的维生素D水平高于异位妊娠组(p = 0.002)。所有患者中,182例患者(60.66%)存在维生素D缺乏,64例患者(21.33%)存在维生素D不足。异位妊娠患者的血清维生素D水平在统计学上低于正常妊娠女性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954c/7072032/34727159462f/JFRH-13-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954c/7072032/34727159462f/JFRH-13-167-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954c/7072032/34727159462f/JFRH-13-167-g001.jpg

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引用本文的文献

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本文引用的文献

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PLoS One. 2017 Jul 24;12(7):e0180483. doi: 10.1371/journal.pone.0180483. eCollection 2017.
2
Characterisation of vitamin D-related molecules and calcium-sensing receptor in human Fallopian tube during the menstrual cycle and in ectopic pregnancy.月经周期及异位妊娠期间人输卵管中维生素D相关分子和钙敏感受体的特征分析
Cell Tissue Res. 2017 Apr;368(1):201-213. doi: 10.1007/s00441-016-2519-2. Epub 2016 Oct 22.
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The prevalence of Chlamydia trachomatis and Mycoplasma genitalium tubal infections and their effects on the expression of IL-6 and leukaemia inhibitory factor in Fallopian tubes with and without an ectopic pregnancy.
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Innate Immun. 2016 Oct;22(7):534-45. doi: 10.1177/1753425916662326. Epub 2016 Aug 10.
4
Effects of 1,25-Dihydroxy Vitamin D3 on Endometriosis.1,25-二羟维生素 D3 对子宫内膜异位症的影响。
J Clin Endocrinol Metab. 2016 Jun;101(6):2371-9. doi: 10.1210/jc.2016-1515. Epub 2016 Apr 1.
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Vitamin D receptor protein is associated with interleukin-6 in human skeletal muscle.维生素D受体蛋白与人类骨骼肌中的白细胞介素-6相关。
Endocrine. 2015 Jun;49(2):512-20. doi: 10.1007/s12020-014-0505-6. Epub 2014 Dec 16.
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