Gordon-Williams Richard, Farquhar-Smith Paul
Department of Pain Medicine, The Royal Marsden NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK.
F1000Res. 2020 Mar 11;9. doi: 10.12688/f1000research.21625.1. eCollection 2020.
Chemotherapy-induced peripheral neuropathy (CIPN) is a common cause of pain and poor quality of life for those undergoing treatment for cancer and those surviving cancer. Many advances have been made in the pre-clinical science; despite this, these findings have not been translated into novel preventative measures and treatments for CIPN. This review aims to give an update on the pre-clinical science, preventative measures, assessment and treatment of CIPN.
化疗引起的周围神经病变(CIPN)是癌症治疗患者及癌症幸存者疼痛和生活质量低下的常见原因。临床前科学已经取得了许多进展;尽管如此,这些研究结果尚未转化为针对CIPN的新型预防措施和治疗方法。本综述旨在介绍CIPN的临床前科学、预防措施、评估和治疗的最新情况。