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本文引用的文献

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Randomized controlled trial of cryotherapy to prevent paclitaxel-induced peripheral neuropathy (RU221511I); an ACCRU trial.随机对照试验研究冷冻疗法预防紫杉醇引起的周围神经病变（RU221511I）；一项 ACCRU 试验。
Breast. 2019 Dec;48:89-97. doi: 10.1016/j.breast.2019.09.011. Epub 2019 Sep 19.
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Targeting Cannabinoid 1 and Delta Opioid Receptor Heteromers Alleviates Chemotherapy-Induced Neuropathic Pain.靶向大麻素1型和δ阿片受体异聚体可减轻化疗引起的神经性疼痛。
ACS Pharmacol Transl Sci. 2019 Aug 9;2(4):219-229. doi: 10.1021/acsptsci.9b00008. Epub 2019 Jun 5.
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Progress in cancer survival, mortality, and incidence in seven high-income countries 1995-2014 (ICBP SURVMARK-2): a population-based study.1995-2014 年七个高收入国家癌症存活率、死亡率和发病率的进展（ICBP SURVMARK-2）：一项基于人群的研究。
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Efficacy of a topical gabapentin gel in a cisplatin paradigm of chemotherapy-induced peripheral neuropathy.局部应用加巴喷丁凝胶治疗顺铂诱导的化疗性周围神经病的疗效。
BMC Pharmacol Toxicol. 2019 Aug 28;20(1):51. doi: 10.1186/s40360-019-0329-3.
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Chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer survivors: a comparison of patient-reported outcomes and quantitative sensory testing.化疗诱导的周围神经病（CIPN）在乳腺癌幸存者中的表现：患者报告结局与定量感觉测试的比较。
Breast Cancer Res Treat. 2019 Dec;178(3):587-595. doi: 10.1007/s10549-019-05416-4. Epub 2019 Aug 27.
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Early changes in tests of peripheral nerve function during oxaliplatin treatment and their correlation with chemotherapy-induced polyneuropathy symptoms and signs.奥沙利铂治疗期间周围神经功能检测的早期变化及其与化疗诱导的多发性神经病症状和体征的相关性。
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Effectiveness of Neurostimulation Technologies for the Management of Chronic Pain: A Systematic Review.神经刺激技术治疗慢性疼痛的疗效：系统评价。
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Rational treatment of chemotherapy-induced peripheral neuropathy with capsaicin 8% patch: from pain relief towards disease modification.使用8%辣椒素贴剂合理治疗化疗引起的周围神经病变：从缓解疼痛到改善病情
J Pain Res. 2019 Jul 3;12:2039-2052. doi: 10.2147/JPR.S213912. eCollection 2019.
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Macrophage Toll-like Receptor 9 Contributes to Chemotherapy-Induced Neuropathic Pain in Male Mice.巨噬细胞 Toll 样受体 9 促进雄性小鼠化疗诱导的神经性疼痛。
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化疗诱导的周围神经病变认识的最新进展

Recent advances in understanding chemotherapy-induced peripheral neuropathy.

作者信息

Gordon-Williams Richard, Farquhar-Smith Paul

机构信息

Department of Pain Medicine, The Royal Marsden NHS Foundation Trust, Fulham Road, London, SW3 6JJ, UK.

出版信息

F1000Res. 2020 Mar 11;9. doi: 10.12688/f1000research.21625.1. eCollection 2020.

DOI:10.12688/f1000research.21625.1
PMID:32201575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7076330/
Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a common cause of pain and poor quality of life for those undergoing treatment for cancer and those surviving cancer. Many advances have been made in the pre-clinical science; despite this, these findings have not been translated into novel preventative measures and treatments for CIPN. This review aims to give an update on the pre-clinical science, preventative measures, assessment and treatment of CIPN.

摘要

化疗引起的周围神经病变（CIPN）是癌症治疗患者及癌症幸存者疼痛和生活质量低下的常见原因。临床前科学已经取得了许多进展；尽管如此，这些研究结果尚未转化为针对CIPN的新型预防措施和治疗方法。本综述旨在介绍CIPN的临床前科学、预防措施、评估和治疗的最新情况。