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Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients.

作者信息

Zheng Hong-Yi, Zhang Mi, Yang Cui-Xian, Zhang Nian, Wang Xi-Cheng, Yang Xin-Ping, Dong Xing-Qi, Zheng Yong-Tang

机构信息

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China.

Yunnan Provincial Hospital of Infectious Diseases, Kunming, 650301, China.

出版信息

Cell Mol Immunol. 2020 May;17(5):541-543. doi: 10.1038/s41423-020-0401-3. Epub 2020 Mar 17.

DOI:10.1038/s41423-020-0401-3
PMID:32203186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7091621/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/7193626/61082b73235d/41423_2020_401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/7193626/61082b73235d/41423_2020_401_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b012/7193626/61082b73235d/41423_2020_401_Fig1_HTML.jpg

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Int J Antimicrob Agents. 2020 Apr;55(4):105946. doi: 10.1016/j.ijantimicag.2020.105946. Epub 2020 Mar 19.
人类和ACE2人源化小鼠对SARS-CoV-2感染的免疫反应。
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