School of Biological Sciences, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region.
J Am Coll Nutr. 2021 Jan;40(1):26-32. doi: 10.1080/07315724.2020.1734990. Epub 2020 Mar 26.
This study investigated the accuracy of a flash glucose monitoring system (FGMS) in a postprandial setting.
Ten fasted adults without diabetes wore the FGMS sensors then consumed a standard breakfast. Their glucose levels were subsequently recorded for 2 hours, both by the FGMS and by measuring capillary glucose levels using the glucose oxidase method. The accuracy of the FGMS data was assessed using the accuracy limits stated in ISO 15197:2013.
FGMS measurements were mostly lower than glucose oxidase measurements (mean absolute relative difference ± : 25.4 ± 17.0%, < 0.001). However, the maximum difference from baseline captured by the two methods was not significantly different (mean ± , glucose oxidase: 58.5 ± 18.9 mg/dl; FGMS, 54.4 ± 28.9 mg/dl, = 0.366).
FGMS could track the incremental glycaemic excursions after meals in adults without diabetes, yet further studies with greater sample sizes are needed to confirm this finding.
本研究旨在探讨即时血糖监测系统(FGMS)在餐后状态下的准确性。
10 名无糖尿病的空腹成年人佩戴 FGMS 传感器,然后食用标准早餐。随后,通过 FGMS 和葡萄糖氧化酶法测量毛细血管血糖水平,分别记录他们 2 小时内的血糖水平。根据 ISO 15197:2013 中的准确度限制评估 FGMS 数据的准确性。
FGMS 测量值大多低于葡萄糖氧化酶测量值(平均绝对相对差异±:25.4±17.0%,<0.001)。然而,两种方法捕捉到的最大与基线差值无显著差异(平均值±,葡萄糖氧化酶:58.5±18.9mg/dl;FGMS:54.4±28.9mg/dl,=0.366)。
FGMS 可在无糖尿病的成年人中追踪餐后的血糖增量波动,但需要更大样本量的进一步研究来证实这一发现。