Department of Aesthetic and Reconstructive Breast Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 33# Badachu Road, Shijingshan District, Beijing, 100144, People's Republic of China.
Aesthetic Plast Surg. 2021 Feb;45(1):118-126. doi: 10.1007/s00266-020-01683-5. Epub 2020 Mar 25.
Autologous fat grafting has been widely used in the field of plastic surgery, especially breast aesthetic augmentation. However, postoperative fat volume retention rate is still difficult to predict.
The authors conducted a retrospective study to compare the fat volume retention rate in patients with varying lactation histories.
A retrospective study was performed of patients who underwent autologous fat grafting breast augmentation in our center from 2012 to 2018. Individuals were separated into two groups according to their lactation history: Group A without a history of lactation and Group B with a history of lactation.
A total of 70 cases (137 breasts) were included (Group A, n = 40; Group B, n = 30). Patients without lactation history were younger (Group A, 25.88 years; Group B, 36.03 years, p < 0.05) and had a significantly lower mean body mass index (Group A,19.72 kg/m; Group B, 20.83 kg/m, p = 0.010). The proportion of donor sites varied (Group A, abdomen 25%, thigh 70%; Group B, abdomen 53.33%, thigh 46.67%, p < 0.05). The percentage of tissue volume retained of patients with a history of lactation was significantly higher (Group A, 30.42%; Group B, 41.03%, p = 0.028).
Significant differences in postoperative volume retention rate in different patients based on lactation history were observed. The volume retention rate after breast augmentation with autologous fat is higher in patients with a history of lactation. The physiological process of lactation may influence the response to autologous fat grafting, but further studies of the mechanism are needed.
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自体脂肪移植在整形美容领域得到了广泛的应用，特别是在乳房美容隆乳术中。然而，术后脂肪体积保留率仍难以预测。
作者进行了一项回顾性研究，比较了不同哺乳史患者的脂肪体积保留率。
对 2012 年至 2018 年在我院行自体脂肪隆乳术的患者进行回顾性研究。根据哺乳史将患者分为两组：A 组无哺乳史，B 组有哺乳史。
共纳入 70 例（137 侧乳房）患者（A 组 40 例，B 组 30 例）。无哺乳史患者年龄较小（A 组 25.88 岁，B 组 36.03 岁，p<0.05），平均体重指数较低（A 组 19.72 kg/m2，B 组 20.83 kg/m2，p=0.010）。供区部位分布不同（A 组腹部 25%，大腿 70%；B 组腹部 53.33%，大腿 46.67%，p<0.05）。有哺乳史患者的组织体积保留率明显较高（A 组 30.42%，B 组 41.03%，p=0.028）。
根据哺乳史观察到不同患者术后体积保留率存在显著差异。有哺乳史的患者自体脂肪隆乳术后体积保留率较高。哺乳的生理过程可能影响对自体脂肪移植的反应，但需要进一步研究其机制。
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