Department of Psychiatry & Behavioral Sciences, MIND Institute, University of California-Davis Health, 2825 50th Street, Sacramento, CA, 95817, USA.
Department of Public Health Sciences, University of California-Davis, Davis, CA, USA.
J Autism Dev Disord. 2021 Mar;51(3):1007-1012. doi: 10.1007/s10803-020-04468-6.
Few studies have explored autism spectrum disorder (ASD) screening in the first year of life. The current investigation examines the psychometric properties of the Infant-Toddler Checklist starting in the first year of life in a sample at elevated and average risk for ASD based on family history. 283 participants were followed from 6 to 36 months, when diagnostic outcome was determined. The results indicated low to moderate sensitivity, specificity, and positive predictive value across ages for broadly distinguishing any delays from typical development, as well as for more narrowly discriminating children with ASD from those who were typically developing. Implications for utilizing ASD screening tools in the first year of life with high risk samples are discussed.
很少有研究探索生命第一年的自闭症谱系障碍（ASD）筛查。本研究基于家族史，在一个具有高风险和平均风险的 ASD 样本中，从生命的第一年开始，检查婴儿-幼儿清单的心理计量学特性。283 名参与者从 6 个月到 36 个月被随访，此时确定了诊断结果。结果表明，在各个年龄段，广泛区分任何与典型发育相关的延迟，以及更准确地区分 ASD 儿童和典型发育儿童的能力，具有低到中等的敏感性、特异性和阳性预测值。讨论了在高风险样本中在生命的第一年使用 ASD 筛查工具的意义。
