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Understanding COVID-19: what does viral RNA load really mean?

作者信息

Joynt Gavin M, Wu William Kk

机构信息

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong.

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong.

出版信息

Lancet Infect Dis. 2020 Jun;20(6):635-636. doi: 10.1016/S1473-3099(20)30237-1. Epub 2020 Mar 27.

DOI:10.1016/S1473-3099(20)30237-1
PMID:32224308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7118539/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133c/7118539/9b19998dd2e9/fx1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133c/7118539/9b19998dd2e9/fx1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/133c/7118539/9b19998dd2e9/fx1_lrg.jpg

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本文引用的文献

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Clinical and virological data of the first cases of COVID-19 in Europe: a case series.欧洲首批 COVID-19 病例的临床和病毒学数据:一项病例系列研究。
Lancet Infect Dis. 2020 Jun;20(6):697-706. doi: 10.1016/S1473-3099(20)30200-0. Epub 2020 Mar 27.
2
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China.中国武汉 2019 年冠状病毒病肺炎患者急性呼吸窘迫综合征和死亡的相关危险因素。
JAMA Intern Med. 2020 Jul 1;180(7):934-943. doi: 10.1001/jamainternmed.2020.0994.
3
SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients.
聚维酮碘鼻腔冲洗和口腔冲洗在 COVID-19 管理中的疗效:一项前瞻性、随机、先导性临床试验(COVID-19 管理中的聚维酮碘)。
BMC Infect Dis. 2024 Mar 1;24(1):271. doi: 10.1186/s12879-024-09137-y.
4
SARS-Cov-2 Cycle Threshold Value and Olfactory Dysfunction in COVID-19 Patients.新冠病毒感染患者中新冠病毒2型的循环阈值与嗅觉功能障碍
Iran J Otorhinolaryngol. 2023 Sep;35(130):263-273. doi: 10.22038/IJORL.2023.71462.3429.
5
Single virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy.宽场离焦增强中红外光热显微镜对单病毒指纹的识别。
Nat Commun. 2023 Oct 20;14(1):6655. doi: 10.1038/s41467-023-42439-4.
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感染患者上呼吸道标本中的新型冠状病毒2型病毒载量
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Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial.地塞米松治疗急性呼吸窘迫综合征:一项多中心、随机对照试验。
Lancet Respir Med. 2020 Mar;8(3):267-276. doi: 10.1016/S2213-2600(19)30417-5. Epub 2020 Feb 7.
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Viral Load Kinetics of MERS Coronavirus Infection.中东呼吸综合征冠状病毒感染的病毒载量动力学
N Engl J Med. 2016 Sep 29;375(13):1303-5. doi: 10.1056/NEJMc1511695.
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Intensive Care Med. 2006 Jul;32(7):1004-13. doi: 10.1007/s00134-006-0134-5. Epub 2006 Mar 29.
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Real-time reverse transcription PCR (qRT-PCR) and its potential use in clinical diagnosis.实时逆转录聚合酶链反应(qRT-PCR)及其在临床诊断中的潜在应用。
Clin Sci (Lond). 2005 Oct;109(4):365-79. doi: 10.1042/CS20050086.
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Emerg Infect Dis. 2004 Feb;10(2):294-9. doi: 10.3201/eid1002.030610.