成年乳糜泻患者的焦虑症状及无麸质饮食的影响：一项伊朗全国性研究
Anxiety Symptoms in Adult Celiac Patients and the Effect of a Gluten-Free Diet: An Iranian Nationwide Study.
作者信息
Rostami-Nejad Mohammad, Taraghikhah Nazanin, Ciacci Carolina, Pourhoseingholi Mohamad Amin, Barzegar Farnoush, Rezaei-Tavirani Mostafa, Aldulaimi David, Zali Mohammad Reza
机构信息
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Student Research Committee, Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Inflamm Intest Dis. 2020 Feb;5(1):42-47. doi: 10.1159/000505657. Epub 2020 Jan 24.
INTRODUCTION
Psychiatric disorders, especially anxiety, are considered extraintestinal manifestations of celiac disease (CD).
OBJECTIVE
This study aims to evaluate the level of anxiety in treated patients with CD in Iran.
METHODS
A total of 283 CD patients (190 female, 93 male) were enrolled in a study during 2016-2018 from 9 centers in Iran. The Zung Self-Rating Anxiety Scale questionnaire was completed. The anxiety index was calculated. Also, demographic data and the duration of treatment with a gluten-free diet (GFD) were recorded. Data were analyzed by SPSS version 20.
RESULTS
Anxiety symptoms were reported in 67.8% of patients. Female patients had a higher anxiety index than male patients. Duration of treatment with a GFD did not influence the anxiety index (17.3% were on a GFD for <1 year, 33.6% for 1-2 years, and 49.1% had GFD for >2 years; = 0.86).
CONCLUSIONS
These results suggest that anxiety symptoms are common among patients, especially females, with CD in Iran and GFD duration has no effect on their improvement.
引言
精神疾病，尤其是焦虑症，被认为是乳糜泻（CD）的肠外表现。
目的
本研究旨在评估伊朗接受治疗的CD患者的焦虑水平。
方法
2016年至2018年期间，从伊朗9个中心招募了总共283名CD患者（190名女性，93名男性）。完成了zung自评焦虑量表问卷。计算焦虑指数。此外，记录了人口统计学数据和无麸质饮食（GFD）的治疗持续时间。数据采用SPSS 20版进行分析。
结果
67.8%的患者报告有焦虑症状。女性患者的焦虑指数高于男性患者。GFD的治疗持续时间对焦虑指数没有影响（17.3%的患者接受GFD治疗<1年，33.6%的患者接受GFD治疗1-2年，49.1%的患者接受GFD治疗>2年；P=0.86）。
结论
这些结果表明，在伊朗，焦虑症状在CD患者中很常见，尤其是女性，并且GFD持续时间对其改善没有影响。
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