Sharifnejad Yeganeh, Amanpour Farzaneh, Rostami Kamran, Rezaie Tavirani Mostafa, Pourhoseingholi Mohamad Amin, Rostami-Nejad Mohammad
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Gastroenterology Palmerston North Hospital, New Zealand.
Gastroenterol Hepatol Bed Bench. 2023;16(2):151-157. doi: 10.22037/ghfbb.v16i2.2134.
This study aimed to detect relationships among quality of life (QoL) and anxiety and demographic factors in patients with celiac disease (CD).
CD is a type of autoimmune small intestine diseases caused by gluten ingestion. In Iran, the prevalence of CD is considered to be 1% in the general population. As physical problems and behavioral disorders of CD can lead to a reduction in QoL.
This cross-sectional study was performed on 533 patients with Celiac Disease from 9 cities of Iran. Data collected were analyzed by SPSS version 22. Quality of life and anxiety respectively evaluated by (GHQ-28) and SAS questionnaires. Predictors of quality of life (sex, age, age of diagnosis, city of life, education level, family history of celiac, occupation and anxiety) were tested by multiple linear regression.
Our results showed a significant relationship between poor quality of life and anxiety (correlation= -0.143, P=0.001). The mean of the quality of life index in celiac diseases was 126.2±30.4 and women had a lower quality of life than men (P=0.003) importantly in emotions and worries scores. There was no significant difference between male and female in terms of anxiety level.
According to the results, both quality of life and anxiety correlated together and women seem to suffer more than men from celiac disease. Therefore, greater attention to women who have celiac disease are suggested.
本研究旨在检测乳糜泻（CD）患者的生活质量（QoL）、焦虑与人口统计学因素之间的关系。
CD是一种由摄入麸质引起的自身免疫性小肠疾病。在伊朗，普通人群中CD的患病率被认为是1%。由于CD的身体问题和行为障碍会导致生活质量下降。
本横断面研究对来自伊朗9个城市的533例乳糜泻患者进行。收集的数据用SPSS 22版进行分析。生活质量和焦虑分别通过（GHQ - 28）和SAS问卷进行评估。生活质量的预测因素（性别、年龄、诊断年龄、生活城市、教育水平、乳糜泻家族史、职业和焦虑）通过多元线性回归进行测试。
我们的结果显示生活质量差与焦虑之间存在显著关系（相关性 = -0.143，P = 0.001）。乳糜泻患者生活质量指数的平均值为126.2±30.4，女性的生活质量低于男性（P = 0.003），在情绪和担忧得分方面尤为重要。男性和女性在焦虑水平方面没有显著差异。
根据结果，生活质量和焦虑相互关联，女性似乎比男性更容易患乳糜泻。因此，建议更加关注患有乳糜泻的女性。
