ICMR-National Institute of Virology, Pune, Maharashtra, India.
Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India.
Indian J Med Res. 2020;151(2 & 3):172-176. doi: 10.4103/ijmr.IJMR_763_20.
Novel coronavirus infection [coronavirus disease 2019 (COVID-19)] has spread to more than 203 countries of various regions including Africa, America, Europe, South East Asia and Western Pacific. The WHO had declared COVID-19 as the global public health emergency and subsequently as pandemic because of its worldwide spread. It is now one of the top-priority pathogens to be dealt with, because of high transmissibility, severe illness and associated mortality, wide geographical spread, lack of control measures with knowledge gaps in veterinary and human epidemiology, immunity and pathogenesis. The quick detection of cases and isolating them has become critical to contain it. To meet the increasing demand of the diagnostic services, it is necessary to enhance and expand laboratory capabilities since existing laboratories cannot meet the emerging demand. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a BSL-2 (Biosafety Level 2) agent and needs to be handled in biosafety cabinet using standard precautions. This review highlights minimum requirements for the diagnostic laboratories opting testing of material for the diagnosis of COVID-19 and associated biorisk to the individuals and to the community.
新型冠状病毒感染(COVID-19)已传播到包括非洲、美洲、欧洲、东南亚和西太平洋在内的 203 个以上的国家和地区。由于其在全球范围内的传播,世界卫生组织(WHO)已宣布 COVID-19为全球公共卫生紧急事件,并随后宣布为大流行。由于其高传染性、严重疾病和相关死亡率、广泛的地理传播、缺乏防控措施以及兽医和人类流行病学、免疫和发病机制方面的知识空白,它现在是需要优先处理的病原体之一。快速检测病例并将其隔离已成为遏制疫情的关键。为了满足日益增长的诊断服务需求,有必要加强和扩大实验室能力,因为现有实验室无法满足新出现的需求。严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是一种生物安全等级 2(BSL-2)的病原体,需要在生物安全柜中使用标准预防措施进行处理。本综述强调了选择用于诊断 COVID-19 及相关生物风险的材料的诊断实验室的最低要求,包括对个人和社区的生物风险。