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Modeling Multiplexed Images with Reveals Novel Tissue Microenvironments.

机构信息

Calico Life Sciences LLC, South San Francisco, California, USA.

Department of Pathology, Stanford University, Stanford, California, USA.

出版信息

J Comput Biol. 2020 Aug;27(8):1204-1218. doi: 10.1089/cmb.2019.0340. Epub 2020 Apr 3.

DOI:10.1089/cmb.2019.0340

PMID:32243203

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7415889/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad3/7415889/2679604e661a/cmb.2019.0340_figure1.jpg

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Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma.

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Modeling Multiplexed Images with Reveals Novel Tissue Microenvironments.

机构信息

Calico Life Sciences LLC, South San Francisco, California, USA.

Department of Pathology, Stanford University, Stanford, California, USA.

出版信息

J Comput Biol. 2020 Aug;27(8):1204-1218. doi: 10.1089/cmb.2019.0340. Epub 2020 Apr 3.

DOI:10.1089/cmb.2019.0340

PMID:32243203

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7415889/

Abstract

摘要

相似文献

Modeling Multiplexed Images with Reveals Novel Tissue Microenvironments.

J Comput Biol. 2020 Aug;27(8):1204-1218. doi: 10.1089/cmb.2019.0340. Epub 2020 Apr 3.

A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging.

Cell. 2018 Sep 6;174(6):1373-1387.e19. doi: 10.1016/j.cell.2018.08.039.

Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer.

Commun Biol. 2021 Jul 9;4(1):852. doi: 10.1038/s42003-021-02361-1.

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers.

J Clin Invest. 2019 Apr 1;129(4):1785-1800. doi: 10.1172/JCI96313. Epub 2019 Mar 18.

Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer.

J Ovarian Res. 2018 May 30;11(1):43. doi: 10.1186/s13048-018-0414-z.

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Mol Oncol. 2023 Oct;17(10):1953-1961. doi: 10.1002/1878-0261.13515. Epub 2023 Sep 11.

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Breast Cancer Res. 2016 May 11;18(1):50. doi: 10.1186/s13058-016-0708-2.

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SpaceBF: Spatial coexpression analysis using Bayesian Fused approaches in spatial omics datasets.

bioRxiv. 2025 Jun 22:2025.03.29.646124. doi: 10.1101/2025.03.29.646124.

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Nat Genet. 2025 Apr;57(4):910-921. doi: 10.1038/s41588-025-02119-z. Epub 2025 Apr 1.

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Identification and characterization of cell niches in tissue from spatial omics data at single-cell resolution.

Nat Commun. 2025 Feb 16;16(1):1693. doi: 10.1038/s41467-025-57029-9.

Spatial Patterning Analysis of Cellular Ensembles (SPACE) finds complex spatial organization at the cell and tissue levels.

Proc Natl Acad Sci U S A. 2025 Feb 11;122(6):e2412146122. doi: 10.1073/pnas.2412146122. Epub 2025 Feb 4.

本文引用的文献

A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging.

Cell. 2018 Sep 6;174(6):1373-1387.e19. doi: 10.1016/j.cell.2018.08.039.

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging.

Cell. 2018 Aug 9;174(4):968-981.e15. doi: 10.1016/j.cell.2018.07.010. Epub 2018 Aug 2.

Functional and Homeostatic Impact of Age-Related Changes in Lymph Node Stroma.

Front Immunol. 2017 Jun 14;8:706. doi: 10.3389/fimmu.2017.00706. eCollection 2017.

Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors.

Immunity. 2016 Jun 21;44(6):1255-69. doi: 10.1016/j.immuni.2016.06.001.

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Immunity. 2013 Oct 17;39(4):782-95. doi: 10.1016/j.immuni.2013.10.003.

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Immunity. 2013 Jul 25;39(1):11-26. doi: 10.1016/j.immuni.2013.07.008.

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Aging Cell. 2008 Mar;7(2):158-67. doi: 10.1111/j.1474-9726.2007.00365.x. Epub 2008 Jan 28.

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome.

Science. 2006 Sep 29;313(5795):1960-4. doi: 10.1126/science.1129139.

The human thymic microenvironment: new approaches to functional analysis.

Semin Immunol. 1999 Feb;11(1):13-21. doi: 10.1006/smim.1998.0148.