Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Faculty of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2020 Jun;83(6):521-523. doi: 10.1097/JCMA.0000000000000319.
As the outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread over the world, the World Health Organization has declared the outbreak of COVID-19 an international public health emergency. Besides typical respiratory symptoms and signs of COVID-19, digestive symptoms and liver injury have been frequently reported during the course of the disease. In this review, we summarized the recent studies reporting of gastrointestinal and liver manifestations during the course of COVID-19. Digestive symptoms, including anorexia, nausea, vomiting, and diarrhea, are not uncommon in patients with COVID-19, and in some cases digestive symptoms may occur in the absence of any respiratory symptoms. Furthermore, SARS-CoV-2 could be detected in the stool of infected patients, implicating the possibility of fecal-oral transmission. Attention should also be paid to monitor liver function during the course of COVID-19, especially in patients with higher disease severity.
随着由严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）引起的 2019 年冠状病毒病（COVID-19）的爆发在全球范围内迅速蔓延，世界卫生组织宣布 COVID-19 爆发为国际公共卫生紧急事件。除了 COVID-19 的典型呼吸道症状和体征外，在疾病过程中还经常报告有消化系统症状和肝损伤。在这篇综述中，我们总结了最近报道的 COVID-19 过程中胃肠道和肝脏表现的研究。在 COVID-19 患者中，消化系统症状（包括厌食、恶心、呕吐和腹泻）并不少见，在某些情况下，即使没有任何呼吸道症状，也可能会出现消化系统症状。此外，在感染患者的粪便中可检测到 SARS-CoV-2，这意味着存在粪-口传播的可能性。在 COVID-19 过程中还应注意监测肝功能，尤其是在疾病严重程度较高的患者中。
