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利尿剂治疗室与心力衰竭失代偿治疗入院的关系。

Diuretic lounge and the impact on hospital admissions for treatment of decompensated heart failure.

机构信息

Department of Cardiology, Royal Free Hospital, Royal Free NHS Foundation Trust, London, UK.

Department of Cardiology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

出版信息

QJM. 2020 Sep 1;113(9):651-656. doi: 10.1093/qjmed/hcaa114.

Abstract

BACKGROUND

Heart failure is a prevalent condition associated with frequent and costly hospital admissions. Hospitalizations are primarily related to worsening fluid retention and often require admission for decongestion with intravenous diuretics.

OBJECTIVE

To assess the safety of an outpatient intravenous diuresis service for heart failure patients, and its impact on emergency admissions and the cost of treatment.

METHODS

We conducted a prospective observational cohort registry study on patients referred to the diuretic lounge at our acute hospital between May 2017 and April 2018.

RESULTS

We analysed 245 patients treated in the diuretic lounge, of which 190 (77.6%) avoided hospitalization or any adverse events during the 60 days of follow up (77.6% vs. 22.4%; P < 0.001). The diuretic lounge service resulted in a significant decrease in emergency heart failure admissions compared to the previous 12 months (823 vs. 715 per annum; 68.6 ± 10.1 vs. 59.6 ± 14 per month; P = 0.04), and a numerical reduction in readmission rates (17.3% vs. 16.2%). The 13.1% decrease in admissions lead to financial savings of £315 497 per annum and £2921 per admission avoided. During the same time period, at the other acute hospital site in our trust, where no diuretic lounge service is available, the number of admissions did not significantly change (457 vs. 450 per annum; 37.5 ± 7.0 vs. 38.1 ± 7.6 per month; P = 0.81).

CONCLUSION

Ambulatory administration of intravenous diuretics reduces emergency admissions and is a safe and cost-effective alternative to treat acute decomposition in heart failure patients.

摘要

背景

心力衰竭是一种常见病症,常导致频繁且昂贵的住院治疗。住院主要与液体潴留恶化有关,且通常需要入院接受静脉利尿剂以消除水肿。

目的

评估心力衰竭患者门诊静脉利尿剂服务的安全性,及其对急诊入院和治疗费用的影响。

方法

我们对 2017 年 5 月至 2018 年 4 月在我们的急症医院利尿剂休息室就诊的患者进行了前瞻性观察队列登记研究。

结果

我们分析了 245 例在利尿剂休息室接受治疗的患者,其中 190 例(77.6%)在 60 天随访期间避免了住院或任何不良事件(77.6%比 22.4%;P<0.001)。与前 12 个月相比,利尿剂休息室服务显著降低了心力衰竭急诊入院率(823 例比 715 例/年;68.6±10.1 例比 59.6±14 例/月;P=0.04),且住院率呈数值性降低(17.3%比 16.2%)。入院人数减少 13.1%,每年可节省 315497 英镑,每次住院可节省 2921 英镑。在此期间,在我们信托基金的另一家急症医院,由于没有利尿剂休息室服务,入院人数没有明显变化(457 例比 450 例/年;37.5±7.0 例比 38.1±7.6 例/月;P=0.81)。

结论

门诊给予静脉利尿剂可减少急诊入院,是治疗心力衰竭急性失代偿的安全且具有成本效益的替代方法。

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