School of Medical Imaging, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People's Republic of China.
Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu, People's Republic of China.
Int J Nanomedicine. 2019 Jul 3;14:4781-4800. doi: 10.2147/IJN.S207666. eCollection 2019.
Advancements in nanotechnology and molecular biology have promoted the development of a diverse range of models to intervene in various disorders (from diagnosis to treatment and even theranostics). Manganese dioxide nanosheets (MnO NSs), a typical two-dimensional (2D) transition metal oxide of nanomaterial that possesses unique structure and distinct properties have been employed in multiple disciplines in recent decades, especially in the field of biomedicine, including biocatalysis, fluorescence sensing, magnetic resonance imaging and cargo-loading functionality. A brief overview of the different synthetic methodologies for MnO NSs and their state-of-the-art biomedical applications is presented below, as well as the challenges and future perspectives of MnO NSs.
纳米技术和分子生物学的进步促进了多种模型的发展，以干预各种疾病（从诊断到治疗，甚至治疗诊断）。二氧化锰纳米片（MnO NSs）是一种典型的二维（2D）过渡金属氧化物纳米材料，具有独特的结构和独特的性质，近几十年来已应用于多个学科，特别是在生物医学领域，包括生物催化、荧光传感、磁共振成像和载药功能。下面简要介绍了 MnO NSs 的不同合成方法及其在生物医学中的最新应用，以及 MnO NSs 的挑战和未来展望。
