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用于将抗菌蛋白递送至生物膜的纳米工程化中空介孔二氧化硅纳米颗粒。

Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms.

作者信息

Xu Chun, He Yan, Li Zhihao, Ahmad Nor Yusilawati, Ye Qingsong

机构信息

School of Dentistry, The University of Queensland, Brisbane, QLD 4072, Australia.

出版信息

J Mater Chem B. 2018 Apr 7;6(13):1899-1902. doi: 10.1039/c7tb03201c. Epub 2018 Mar 20.

DOI:10.1039/c7tb03201c
PMID:32254355
Abstract

The delivery of bactericidal proteins into biofilms is challenging. Hollow mesoporous silica nanoparticles with large cone-shaped pores were synthesized to deliver antimicrobial proteins into biofilms and showed enhanced antimicrobial activities.

摘要

将杀菌蛋白递送至生物被膜具有挑战性。合成了具有大锥形孔的中空介孔二氧化硅纳米颗粒，以将抗菌蛋白递送至生物被膜，并显示出增强的抗菌活性。

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